The Pharmacological Properties and Therapeutic Use of Bitter Melon (Momordica charantia L.)

Abstract

Background

Momordica charantia L., a typical vegetable with multiple medicinal properties, is widely culti-vated around the world.

Research contents

Anti-diabetic, anti-obesity, anti-cancer, anti-microbial, hypotensive, antioxidant, anti-hyperlipidemic, anti-inflammatory, immunomodulatory, anthelmintic, and protective properties have been well clarified both in vitro and in vivo, which might be due to various phytochemicals, such as carbohydrates, protein, fatty acids, amino acids, phenolic acids, minerals, essential oils, alkaloids, vitamins, flavonoids, and triterpenoids.

Significance

This review summarizes the active components and medicinal properties of different parts of M. charantia, especially the anti-diabetic and anti-cancer properties, aiming to highlight the medicinal usage of M. charantia and provide valuable references for the development of M. charantia as multifunctional food and medicine.

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Acknowledgments

This work was supported by research grants from Huanggang Normal University (2014022203) and Foreign Cooperation Project of Hubei Science and Technology Department (2014BHE036).

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Correspondence to Shuzhen Wang.

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Li, Z., Xia, A., Li, S. et al. The Pharmacological Properties and Therapeutic Use of Bitter Melon (Momordica charantia L.). Curr Pharmacol Rep 6, 103–109 (2020). https://doi.org/10.1007/s40495-020-00219-4

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Keywords

  • Momordica charantia L.
  • Traditional medicine
  • Therapeutic use
  • Pharmacological properties
  • Therapeutic use