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Characteristic Components, Biological Activities and Future Prospective of Fructus Mori: a Review

  • Natural Products: From Chemistry to Pharmacology (C Ho, Section Editor)
  • Published:
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Abstract

Purpose of Review

China has a long history in planting mulberry with the most varieties and the largest production in the world. This article provides a brief overview of an important edible fruit and traditional medicine in China—Fructus Mori (FM, mulberry fruit or Morus alba L. fruit), including the main chemical constituents, major bioactivities and the future prospective.

Recent Findings

Phytochemical studies have revealed that Fructus Mori contains a great diversity of nutritive compounds such as organic acids, amino acids, vitamins, minerals, and bioactive components, including polysaccharides, polyphenolics, anthocyanins, flavonoids, alkaloids, stilbenes, and diels-alder type adducts. Besides, the extracts and active components of FM were reported to have numerous biological activities, including antioxidant, antihyperglycemic, antitumor, hepatoprotective, and neuroprotective activities in in vitro and in vivo studies.

Summary

This review provides recent findings systematically regarding the structural characteristics and biological activities of FM, which may be useful for stimulating deep research of therapeutic potentials and for predicting their uses as important and safe functional foods to benefit human health.

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Acknowledgements

We’d also like to thank the journal’s editor-in-chief, Tony Kong, for reviewing the article.

Funding

This study was supported by the National Natural Science Foundation of China (No. 31570348).

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Authors and Affiliations

  1. College of Food Science and Engineering, Northwest University, 229 Taibai North Road, Xi’an, 710069, Shaanxi, China

    Sen Guo, Lu Bai & Naisheng Bai

  2. College of Chemical Engineering, Department of Pharmaceutical Engineering, Northwest University, 229 Taibai North Road, Xi’an, 710069, Shaanxi, China

    Sen Guo

  3. Department of Food Science, Rutgers University, 65 Dudley Road, New Brunswick, NJ, 08901, USA

    Chi-Tang Ho

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  1. Sen Guo
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  2. Lu Bai
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Correspondence to Naisheng Bai.

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Sen Guo, Lu Bai, Chi-Tang Ho, and Naisheng Bai declare no conflict of interest.

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Guo, S., Bai, L., Ho, CT. et al. Characteristic Components, Biological Activities and Future Prospective of Fructus Mori: a Review. Curr Pharmacol Rep 4, 210–219 (2018). https://doi.org/10.1007/s40495-018-0135-4

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