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Quantitative Biology

, Volume 5, Issue 2, pp 136–142 | Cite as

Current progresses of 3D bioprinting based tissue engineering

  • Zeyu Zhang
  • Xiu-Jie Wang
Review
  • 670 Downloads

Abstract

Background

The shortage of available organs for transplantation is the major obstacle hindering the application of regenerative medicine, and has also become the desperate problem faced by more and more patients nowadays. The recent development and application of 3D printing technique in biological research (bioprinting) has revolutionized the tissue engineering methods, and become a promising solution for tissue regeneration.

Results

In this review, we summarize the current application of bioprinting in producing tissues and organoids, and discuss the future directions and challenges of 3D bioprinting.

Conclusions

Currently, 3D bioprinting is capable to generate patient-specialized bone, cartilage, blood vascular network, hepatic unit and other simple components/tissues, yet pure cell-based functional organs are still desired.

Notes

Acknowledgements

This work is supported by grants 31271349 from the National Natural Science Foundation of China, China 973 Program 2014CB964901 and CAS Strategic Priority Research Program grant XDA01020105.

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Copyright information

© Higher Education Press and Springer-Verlag GmbH 2017

Authors and Affiliations

  1. 1.Key Laboratory of Genetic Network Biology, Collaborative Innovation Center of Genetics and Development, Institute of Genetics and Developmental BiologyChinese Academy of SciencesBeijingChina
  2. 2.University of Chinese Academy of SciencesBeijingChina

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