Current Tropical Medicine Reports

, Volume 5, Issue 1, pp 31–40 | Cite as

A Review on Prevention Interventions to Decrease Diarrheal Diseases’ Burden in Children

  • Camille Webb
  • Miguel M. Cabada
Pediatric Global Health (D Nguyen and A Mandalakas, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Pediatric Global Health


Purpose of Review

Provide an overview about childhood diarrhea burden and prevention interventions with demonstrated impact in reducing disease risk.

Recent Findings

Diarrhea incidence and mortality in children is declining around the world. A few pathogens cause most of the burden (rotavirus, norovirus, Shigella, enterotoxigenic E. coli, Campylobacter, and Cryptosporidium). Available rotavirus vaccines have demonstrated to significantly decrease diarrhea hospital admissions and mortality. WASH interventions, especially point of use water safety improvements and handwashing, are effective in decreasing diarrhea burden. Early and exclusive breastfeeding prevents early childhood diarrhea.


Diarrhea in children under 5 years old is still among the most important causes of mortality in middle- and low-income countries. However, diarrhea complications and deaths are preventable. Vaccines, water, sanitation, and hygiene (WASH) and breastfeeding are effective and affordable interventions. Future research should determine the effectiveness of combining these interventions and address problems in implementation and integration of interventions.


Diarrhea Vaccines WASH Nutrition 


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance•• Of major importance

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Infectious Diseases, Department of Internal MedicineUniversity of Texas Medical BranchGalvestonUSA
  2. 2.Universidad Peruana Cayetano Heredia and University of Texas Medical Branch Collaborative Research Center, Universidad Peruana Cayetano HerediaCuscoPeru

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