Current Transplantation Reports

, Volume 5, Issue 2, pp 130–138 | Cite as

Simultaneous Liver-Kidney Transplantation: Policy Update and the Challenges Ahead

  • Mark I. Aeder
OPTN Policy (K Andreoni, Section Editor)
Part of the following topical collections:
  1. Topical Collection on OPTN Policy


Purpose of the Review

Institution of a Simultaneous Liver Kidney (SLK) policy by the OPTN in 2016 represented the culmination of more than a decade of consensus conferences, public comments, and inter-society cooperation. The debates produced a multi-tiered proposal that established medical eligibility criteria for kidney allocation, a requirement for the regional sharing of a kidney to a MELD 35 medical eligible candidate and creation of a safety net for patients receiving a liver-alone transplant with subsequent kidney failure within the first post transplant year.

Recent Interventions

The stratifications and alterations represented the first time that eligibility requirements have been instituted for allocating a multi-organ combination that is not tracked by the Scientific Registry of Transplant Recipients (SRTR). The provisions for reporting and follow-up of the allocation alteration have been identified and will be reported at regular intervals to the OPTN for public release. Although there are multiple interventions to limit the kidney utilization to those candidates with true medical necessity, it is unknown how this will impact the overall distribution of the kidneys, especially with the safety net now being offered to candidates that would not have met medical eligibility at the time of their transplant. As SLK comprises over 10% of all liver transplants, the requirement change may be significant and would hopefully result in the more efficient use of kidneys without a negative impact on patient survival. Although utilization would be much better monitored, the outcome measures would still be lacking.


Even with this landmark change, review of the allocation process that presently favors allocating a kidney to a multi-organ transplant before allocation to a kidney-alone recipient is examined, especially as the prioritization affects pediatric candidates. It is hoped that advancements in this area would bring allocation policies into greater alignment with the intentions of the Final Rule legislation.


Simultaneous liver-kidney transplantation Multi-organ transplantation UNOS medical eligibility policy Kidney allocation Kidney safety net Liver-kidney transplant outcomes 


Compliance with Ethical Standards

Conflict of Interest

The author declares that he has no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Transplantation, Department of Surgery, Case Western Reserve UniversityUniversity Hospitals Cleveland Medical CenterClevelandUSA

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