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Long-Term Exposure to Ambient Air Pollution and Type 2 Diabetes in Adults

  • Environmental Epidemiology (F Laden and J Hart, Section Editors)
  • Published:
Current Epidemiology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

We identified 24 publications from January 2010 until September 2018 in the peer-reviewed literature addressing the relationship of long-term air pollution exposures and type 2 diabetes-related morbidity and mortality among adults. We examine key methodological issues, synthesize findings, and address study strengths and limitations. We also discuss biological mechanisms, policy implications, and future research needed to address existing knowledge gaps.

Recent Findings

In general, the studies included in this review employed rigorous methodology with large sample sizes, appropriate study designs to maximize available cohort study or administrative data sources, and exposure modeling that accounted for spatial patterns in air pollution levels. Overall, studies suggested increased risks of type 2 diabetes-related morbidity and mortality among adults associated with increased exposures; however, findings were not uniformly positive nor statistically significant.

Summary

Current research is particularly limited regarding the biological mechanisms involved and the relationship between ozone and diabetes. Additionally, more research is needed to distinguish clearly the effects of nitrogen oxides from those of other pollutants and to identify potential subpopulations with greater susceptibility for certain pollutant exposures. A better understanding of the potential link between long-term ambient air pollution exposures and type 2 diabetes may provide opportunities for the reduction of health risks and inform future interventions for environmental protection and diabetes management.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Maryland Institute for Applied Environmental Health, University of Maryland School of Public Health, College Park, MD, USA

    Robin C. Puett, Lesliam Quirós-Alcalá, Jessica A Montresor-López & Devon Payne-Sturges

  2. STEM Library, University of Maryland, College Park, MD, USA

    Nedelina Tchangalova

  3. Department of Medicine, University of Chicago, Chicago, IL, USA

    Anindita Dutta

  4. Division of Epidemiology, Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, USA

    Jeff D. Yanosky

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  1. Robin C. Puett
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Correspondence to Robin C. Puett.

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Robin Puett received an honorarium and travel expenses to present part of this work at the Health Effects Institute Conference in April 2018. Lesliam Quiros-Alcala, Jessica Montresor-Lopez, Nedelina Tchangalova, Anindita Dutta, Devon Payne-Sturges and Jeff Yanosky each declare no potential conflicts of interest.

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Puett, R.C., Quirós-Alcalá, L., Montresor-López, J. et al. Long-Term Exposure to Ambient Air Pollution and Type 2 Diabetes in Adults. Curr Epidemiol Rep 6, 67–79 (2019). https://doi.org/10.1007/s40471-019-0184-1

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