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Cigarette Smoking and Psychiatric Illness Among Individuals with COPD: a Systematic Review

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Abstract

Purpose of Review

Both smoking and psychiatric illness are independently associated with poorer COPD-related health outcomes, but little is known about the course of COPD among people who smoke and have co-occurring psychiatric illness. This systematic review assessed the links between tobacco smoking and psychiatric illness among individuals with COPD.

Recent Findings

Depression and anxiety disorders are positively related with current smoking, nicotine dependence, cigarette use for at least 10 pack-years, and mortality risk among patients with COPD. Several studies also identified schizophrenia as an independent risk factor for incident COPD, after adjusting for smoking history.

Summary

There was an association between depression, anxiety, and schizophrenia with tobacco smoking in COPD. Additional research should examine relationships between other psychiatric illnesses (e.g., personality disorders, PTSD) and tobacco smoking and track COPD-related symptom change over time as a function of smoking cigarettes or newer nicotine products (e.g., e-cigarettes) and with smoking cessation.

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Data Availability

We did not analyze or generate any new data for this review paper. The information summarized in this paper came from previously published papers and authors of individual papers should be contacted directly with regard to their data.

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Acknowledgements

Some data included in this manuscript were presented at the 2019 and at the 2023 meetings for the Society for Research on Nicotine and Tobacco.

Funding

NIH grant R21-DA-043949 to TPG. The NIH had no role in the design, analysis, interpretation, or publication of this study.

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Authors and Affiliations

  1. Ferkauf Graduate School of Psychology, Yeshiva University, 1165 Morris Park Ave, Bronx, NY, 10461, USA

    Jacob Levin, David Estey, Ester Yadgaran, Esther Perez, Isabella Plotnick, Jennifer Gittleman, Joseph Friedman, Silvana Agterberg, Sylvie Messer, Tyler Pia, Jennifer Birchwale, Joun Lee, Lisa N. Cruz, Natacha A. Gordon, Rachel S. Kashan, Jung-Yun Min, Kate S. Segal & Andrea H. Weinberger

  2. Department of Psychology, Fordham University, Bronx, NY, USA

    Joun Lee

  3. D. Samuel Gottesman Library, Albert Einstein College of Medicine, Bronx, NY, USA

    Caroline Delbourgo Patton

  4. Department of Psychiatry, Temerty Faculty of Medicine, Centre for Complex Interventions and Addictions Division, Centre for Addiction and Mental Health (CAMH), University of Toronto, Toronto, Canada

    Tony P. George

  5. Departments of Epidemiology & Population Health and Psychiatry & Behavioral Sciences, Albert Einstein College of Medicine, Bronx, NY, USA

    Andrea H. Weinberger

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Ethical Approval

The Section Editors for the topical collection Dual Diagnosis are Tony George and Victor Tang. Please note that Section Editor Tony George was not involved in the editorial process of this article as he is a co-author.

Conflict of Interest

The authors have no conflicts of interest to report. Financial disclosures are listed below. Jacob Levin reports no financial relationship with commercial interests. Dr. David Estey reports no financial relationship with commercial interests. Ester Yadgaran reports no financial relationship with commercial interests. Esther Perez reports no financial relationship with commercial interests. Isabella Plotnick reports no financial relationship with commercial interests. Jennifer Gittleman reports no financial relationship with commercial interests. Joseph Friedman reports no financial relationship with commercial interests. Silvana Agterberg reports no financial relationship with commercial interests. Sylvie Messer reports no financial relationship with commercial interests. Dr. Jennifer Birchwale reports no financial relationship with commercial interests. Tyler Pia reports no financial relationship with commercial interests. Joun Lee reports no financial relationship with commercial interests. Lisa N. Cruz reports no financial relationship with commercial interests. Natacha Gordon reports no financial relationship with commercial interests. Dr. Rachel Kashan reports no financial relationship with commercial interests. Jung-Yun Min reports no financial relationship with commercial interests. Dr. Kate Segal reports no financial relationship with commercial interests. Caroline Delbourgo Patton reports no financial relationship with commercial interests. Dr. Tony George has been a consultant to Aelis, Frutarom and Stanford, Burhham Prebys, and Chair of the Scientific Advisory Committee of the Canadian Centre for Substance Use and Addictions (CCSA). He also serves as co-Principal Editor, Neuropsychopharmacology. Dr. Andrea Weinberger reports receiving compensation in 2022 from American Institutes for Research for work on an academic chapter.

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This work is a systematic review, which does not involve human subjects, and therefore, no ethical approval is required.

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Jacob Levin and David Estey are co-first authors.

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Levin, J., Estey, D., Yadgaran, E. et al. Cigarette Smoking and Psychiatric Illness Among Individuals with COPD: a Systematic Review. Curr Addict Rep 11, 19–54 (2024). https://doi.org/10.1007/s40429-023-00532-0

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