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Current Research on Cigarette Smoking Among People with HIV

  • Tobacco (A Weinberger, Section Editor)
  • Published:
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Abstract

A large percentage of people with HIV are current cigarette smokers. Most smokers with HIV are interested in quitting; however, smoking cessation interventions are only moderately effective in this population. Also, most HIV care providers are not trained in tobacco dependence treatment and most smokers with HIV are not getting the smoking cessation support that they need. Although advances in HIV treatment have provided the opportunity for prolonged life, many HIV-positive individuals are not benefitting from these advances because they are suffering from the health consequences of tobacco dependence. Barriers to smoking cessation among smokers with HIV need more research, and new interventions that address the unique issues of smokers with HIV need to be developed and evaluated. HIV care providers need education on tobacco dependence treatment so that smokers with HIV have access to the education and support that they need to successfully quit smoking.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance

  1. Mdodo R, Frazier EL, Dube SR, Mattson CL, Sutton MY, Brooks JT, et al. Cigarette smoking prevalence among adults with HIV compared with the general adult population in the United States: cross-sectional surveys. Ann Intern Med. 2015;162(5):335–44. This is the most recent very large study of smoking prevalence among people with HIV.

    Article  PubMed  Google Scholar 

  2. Pacek LR, Harrell PT, Martins SS. Cigarette smoking and drug use among a nationally representative sample of HIV-positive individuals. Am J Addict. 2014;23(6):582–90.

    Article  PubMed  Google Scholar 

  3. Vijayaraghavan M, Penko J, Vittinghoff E, Bangsberg DR, Miaskowski C, Kushel MB. Smoking behaviors in a community-based cohort of HIV-infected indigent adults. AIDS Behav. 2014;18(3):535–43.

    Article  PubMed Central  PubMed  Google Scholar 

  4. Marshall MM, Kirk GD, Caporaso NE, McCormack MC, Merlo CA, Hague JC, et al. Tobacco use and nicotine dependence among HIV-infected and uninfected injection drug users. Addict Behav. 2011;36(1-2):61–7.

    Article  PubMed Central  PubMed  Google Scholar 

  5. Tami-Maury I, Vidrine DJ, Fletcher FE, Danysh H, Arduino R, Gritz ER. Poly-tobacco use among HIV-positive smokers: implications for smoking cessation efforts. Nicotine Tob Res. 2013;15(12):2100–6.

    Article  PubMed Central  PubMed  Google Scholar 

  6. Shuter J, Bernstein SL, Moadel AB. Cigarette smoking behaviors and beliefs in persons living with HIV/AIDS. Am J Health Behav. 2012;36(1):75–85.

    Article  PubMed Central  PubMed  Google Scholar 

  7. Helleberg M, Afzal S, Kronborg G, Larsen CS, Pedersen G, Pedersen C, et al. Mortality attributable to smoking among HIV-1-infected individuals: a nationwide, population-based cohort study. Clin Infect Dis. 2013;56(5):727–34.

    Article  PubMed  Google Scholar 

  8. Lifson AR, Neuhaus J, Arribas JR, van den Berg-Wolf M, Labriola AM, Read TR. Smoking-related health risks among persons with HIV in the strategies for management of antiretroviral therapy clinical trial. Am J Public Health. 2010;100(10):1896–903.

    Article  PubMed Central  PubMed  Google Scholar 

  9. Helleberg M, May MT, Ingle SM, Dabis F, Reiss P, Fatkenheuer G, et al. Smoking and life expectancy among HIV-infected individuals on antiretroviral therapy in Europe and North America. AIDS. 2015;29(2):221–9.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  10. Shuter J, Bernstein SL. Cigarette smoking is an independent predictor of nonadherence in HIV-infected individuals receiving highly active antiretroviral therapy. Nicotine Tob Res. 2008;10(4):731–6.

    Article  CAS  PubMed  Google Scholar 

  11. Centers for Disease Control and Prevention. Current cigarette smoking among adults—United States, 2005–2013. Morb Mortal Wkly Rep. 2014;63(47):1108–12.

    Google Scholar 

  12. Conley LJ, Bush TJ, Buchbinder SP, Penley KA, Judson FN, Holmberg SD. The association between cigarette smoking and selected HIV-related medical conditions. AIDS. 1996;10(10):1121–6.

    CAS  PubMed  Google Scholar 

  13. Burns DN, Hillman D, Neaton JD, Sherer R, Mitchell T, Capps L, et al. Cigarette smoking, bacterial pneumonia, and other clinical outcomes in HIV-1 infection. Terry Beirn Community Programs for Clinical Research on AIDS. J Acquir Immune Defic Syndr Hum Retrovirol. 1996;13(4):374–83.

    Article  CAS  PubMed  Google Scholar 

  14. De P, Farley A, Lindson N, Aveyard P. Systematic review and meta-analysis: influence of smoking cessation on incidence of pneumonia in HIV. BMC Med. 2013;11:15.

    Article  PubMed Central  PubMed  Google Scholar 

  15. Calvo-Sanchez M, Perello R, Perez I, Mateo MG, Junyent M, Laguno M, et al. Differences between HIV-infected and uninfected adults in the contributions of smoking, diabetes and hypertension to acute coronary syndrome: two parallel case-control studies. HIV Med. 2013;14(1):40–8.

    Article  CAS  PubMed  Google Scholar 

  16. Kooij KW, Wit FW, Bisschop PH, Schouten J, Stolte IG, Prins M, et al. Low bone mineral density in patients with well-suppressed HIV infection: association with body weight, smoking, and prior advanced HIV disease. J Infect Dis. 2015;211(4):539–48.

    Article  PubMed  Google Scholar 

  17. Madeddu G, Fois AG, Calia GM, Babudieri S, Soddu V, Becciu F, et al. Chronic obstructive pulmonary disease: an emerging comorbidity in HIV-infected patients in the HAART era? Infection. 2013;41(2):347–53.

    Article  CAS  PubMed  Google Scholar 

  18. Helleberg M, Gerstoft J, Afzal S, Kronborg G, Larsen CS, Pedersen C, et al. Risk of cancer among HIV-infected individuals compared to the background population: impact of smoking and HIV. AIDS. 2014;28(10):1499–508.

    Article  PubMed  Google Scholar 

  19. Chattopadhyay A, Patton LL. Smoking as a risk factor for oral candidiasis in HIV-infected adults. J Oral Pathol Med : Off Publ Int Assoc Oral Pathol Am Acad Oral Pathol. 2013;42(4):302–8.

    Article  Google Scholar 

  20. Pines H, Koutsky L, Buskin S. Cigarette smoking and mortality among HIV-infected individuals in Seattle, Washington (1996-2008). AIDS Behav. 2011;15(1):243–51.

    Article  PubMed  Google Scholar 

  21. Robinson WT, Brown MC, Moody-Thomas S. Smoking and experiences with tobacco cessation among men who have sex with men: New Orleans, 2011. AIDS Behav. 2014;18 Suppl 3:324–32.

    Article  PubMed  Google Scholar 

  22. Akhtar-Khaleel WZ, Cook RL, Shoptaw S, Surkan P, Stall R, Beyth RJ, et al. Trends and predictors of cigarette smoking among HIV seropositive and seronegative men: the multicenter aids cohort study. AIDS Behav. 2015.

  23. Yan AF, Chiu YW, Stoesen CA, Wang MQ. STD-/HIV-related sexual risk behaviors and substance use among U.S. rural adolescents. J Natl Med Assoc. 2007;99(12):1386–94.

    PubMed Central  PubMed  Google Scholar 

  24. Parkes A, Wight D, Henderson M, Hart G. Explaining associations between adolescent substance use and condom use. J Adolesc Health. 2007;40(2):180. e1-18.

    Article  PubMed  Google Scholar 

  25. Hansen BT, Hagerup-Jenssen M, Kjaer SK, Munk C, Tryggvadottir L, Sparen P, et al. Association between smoking and genital warts: longitudinal analysis. Sex Transm Infect. 2010;86(4):258–62.

    Article  PubMed  Google Scholar 

  26. Richter KP, Ahluwalia HK, Mosier MC, Nazir N, Ahluwalia JS. A population-based study of cigarette smoking among illicit drug users in the United States. Addiction. 2002;97(7):861–9.

    Article  PubMed  Google Scholar 

  27. Centers for Disease Control and Prevention: new HIV infections in the United States. http://www.cdc.gov/nchhstp/newsroom/docs/2012/HIV-Infections-2007-2010.pdf (2012). Accessed October 18, 2015.

  28. Schultz AS, Temple B, Gibbons C, Preston J, Ronson G. Listening to those who are living with HIV and tobacco dependence and exploring their health care context. J Assoc Nurses AIDS Care. 2014;25(1):46–59.

    Article  PubMed  Google Scholar 

  29. Pacek LR, Latkin C, Crum RM, Stuart EA, Knowlton AR. Current cigarette smoking among HIV-positive current and former drug users: associations with individual and social characteristics. AIDS Behav. 2014;18(7):1368–77.

    Article  PubMed Central  PubMed  Google Scholar 

  30. Stanton CA, Moadel AB, Kim RS, Weinberger AH, Shuter J. Loneliness in HIV-infected smokers. AIDS Care. 2015;27(2):268–72.

    Article  PubMed Central  PubMed  Google Scholar 

  31. King RM, Vidrine DJ, Danysh HE, Fletcher FE, McCurdy S, Arduino RC, et al. Factors associated with nonadherence to antiretroviral therapy in HIV-positive smokers. AIDS Patient Care STDS. 2012;26(8):479–85.

    Article  PubMed  Google Scholar 

  32. Pacek LR, Latkin C, Crum RM, Stuart EA, Knowlton AR. Interest in quitting and lifetime quit attempts among smokers living with HIV infection. Drug Alcohol Depend. 2014;138:220–4.

    Article  PubMed Central  PubMed  Google Scholar 

  33. Schafer J, Young J, Bernasconi E, Ledergerber B, Nicca D, Calmy A, et al. Predicting smoking cessation and its relapse in HIV-infected patients: the Swiss HIV Cohort Study. HIV Med. 2014.

  34. Hessol NA, Weber KM, D’Souza G, Burton D, Young M, Milam J, et al. Smoking cessation and recidivism in the Women’s Interagency Human Immunodeficiency Virus Study. Am J Prev Med. 2014;47(1):53–69.

    Article  PubMed Central  PubMed  Google Scholar 

  35. Cropsey KL, Jardin BF, Burkholder GA, Clark CB, Raper JL, Saag MS. An algorithm approach to determining smoking cessation treatment for persons living with HIV/AIDS: results of a pilot trial. J Acquir Immune Defic Syndr. 2015;69(3):291–8.

    Article  CAS  PubMed  Google Scholar 

  36. Stanton CA, Papandonatos GD, Shuter J, Bicki A, Lloyd-Richardson EE, de Dios MA, et al. Outcomes of a tailored intervention for cigarette smoking cessation among Latinos living with HIV/AIDS. Nicotine Tob Res. 2015;17(8):975–82. This study is one of five known large randomized controlled trials of a smoking cessation intervention among smokers with HIV.

    Article  PubMed  Google Scholar 

  37. Chew D, Steinberg MB, Thomas P, Swaminathan S, Hodder SL. Evaluation of a smoking cessation program for HIV infected individuals in an urban HIV clinic: challenges and lessons learned. AIDS Res Treat. 2014;2014:237834.

    PubMed Central  PubMed  Google Scholar 

  38. Shuter J, Morales DA, Considine-Dunn SE, An LC, Stanton CA. Feasibility and preliminary efficacy of a web-based smoking cessation intervention for HIV-infected smokers: a randomized controlled trial. J Acquir Immune Defic Syndr. 2014;67(1):59–66.

    Article  PubMed Central  PubMed  Google Scholar 

  39. Healey LM, Michaels C, Bittoun R, Templeton DJ. Efficacy and acceptability of an intervention for tobacco smoking cessation in HIV-positive individuals at a public sexual health clinic. Sex Transm Infect. 2015;91(2):105.

    Article  CAS  PubMed  Google Scholar 

  40. Cropsey KL, Hendricks PS, Jardin B, Clark CB, Katiyar N, Willig J, et al. A pilot study of screening, brief intervention, and referral for treatment (SBIRT) in non-treatment seeking smokers with HIV. Addict Behav. 2013;38(10):2541–6.

    Article  PubMed Central  PubMed  Google Scholar 

  41. Ferketich AK, Diaz P, Browning KK, Lu B, Koletar SL, Reynolds NR, et al. Safety of varenicline among smokers enrolled in the lung HIV study. Nicotine Tob Res. 2013;15(1):247–54.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  42. Humfleet GL, Hall SM, Delucchi KL, Dilley JW. A randomized clinical trial of smoking cessation treatments provided in HIV clinical care settings. Nicotine Tob Res. 2013;15(8):1436–45. This study is one of five known large randomized controlled trials of a smoking cessation intervention among smokers with HIV.

    Article  PubMed Central  PubMed  Google Scholar 

  43. Matthews AK, Conrad M, Kuhns L, Vargas M, King AC. Project Exhale: preliminary evaluation of a tailored smoking cessation treatment for HIV-positive African American smokers. AIDS Patient Care STDS. 2013;27(1):22–32.

    Article  PubMed  Google Scholar 

  44. Manuel JK, Lum PJ, Hengl NS, Sorensen JL. Smoking cessation interventions with female smokers living with HIV/AIDS: a randomized pilot study of motivational interviewing. AIDS Care. 2013;25(7):820–7.

    Article  PubMed Central  PubMed  Google Scholar 

  45. Moadel AB, Bernstein SL, Mermelstein RJ, Arnsten JH, Dolce EH, Shuter J. A randomized controlled trial of a tailored group smoking cessation intervention for HIV-infected smokers. J Acquir Immune Defic Syndr. 2012;61(2):208–15. This study is one of five known large randomized controlled trials of a smoking cessation intervention among smokers with HIV.

    Article  PubMed Central  PubMed  Google Scholar 

  46. Vidrine DJ, Marks RM, Arduino RC, Gritz ER. Efficacy of cell phone-delivered smoking cessation counseling for persons living with HIV/AIDS: 3-month outcomes. Nicotine Tob Res. 2012;14(1):106–10. This study is one of five known large randomized controlled trials of a smoking cessation intervention among smokers with HIV.

    Article  PubMed Central  PubMed  Google Scholar 

  47. Gritz ER, Danysh HE, Fletcher FE, Tami-Maury I, Fingeret MC, King RM, et al. Long-term outcomes of a cell phone-delivered intervention for smokers living with HIV/AIDS. Clin Infect Dis. 2013;57(4):608–15.

    Article  PubMed Central  PubMed  Google Scholar 

  48. Cui Q, Robinson L, Elston D, Smaill F, Cohen J, Quan C, et al. Safety and tolerability of varenicline tartrate (Champix((R))/Chantix((R))) for smoking cessation in HIV-infected subjects: a pilot open-label study. AIDS Patient Care STDS. 2012;26(1):12–9.

    Article  PubMed Central  PubMed  Google Scholar 

  49. Lloyd-Richardson EE, Stanton CA, Papandonatos GD, Shadel WG, Stein M, Tashima K, et al. Motivation and patch treatment for HIV+ smokers: a randomized controlled trial. Addiction. 2009;104(11):1891–900. This study is one of five known large randomized controlled trials of a smoking cessation intervention among smokers with HIV.

    Article  PubMed Central  PubMed  Google Scholar 

  50. Browning KK, Wewers ME, Ferketich AK, Diaz P, Koletar SL, Reynolds NR. Adherence to tobacco dependence treatment among HIV-infected smokers. AIDS Behav. 2015.

  51. Stanton CA, Lloyd-Richardson EE, Papandonatos GD, de Dios MA, Niaura R. Mediators of the relationship between nicotine replacement therapy and smoking abstinence among people living with HIV/AIDS. AIDS Educ Prev. 2009;21(3 Suppl):65–80.

    Article  PubMed Central  PubMed  Google Scholar 

  52. Vidrine DJ, Kypriotakis G, Li L, Arduino RC, Fletcher FE, Tami-Maury I, et al. Mediators of a smoking cessation intervention for persons living with HIV/AIDS. Drug Alcohol Depend. 2015;147:76–80.

    Article  PubMed Central  PubMed  Google Scholar 

  53. Shuter J, Salmo LN, Shuter AD, Nivasch EC, Fazzari M, Moadel AB. Provider beliefs and practices relating to tobacco use in patients living with HIV/AIDS: a national survey. AIDS Behav. 2012;16(2):288–94. This is the only known large national survey of HIV care provider tobacco dependence treatment practices.

    Article  PubMed Central  PubMed  Google Scholar 

  54. Horvath KJ, Eastman M, Prosser R, Goodroad B, Worthington L. Addressing smoking during medical visits: patients with human immunodeficiency virus. Am J Prev Med. 2012;43(5 Suppl 3):S214–21.

    Article  PubMed  Google Scholar 

  55. Huber M, Ledergerber B, Sauter R, Young J, Fehr J, Cusini A, et al. Outcome of smoking cessation counselling of HIV-positive persons by HIV care physicians. HIV Med. 2012;13(7):387–97.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Nina A. Cooperman.

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Nina Cooperman declares no conflict of interest.

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Cooperman, N.A. Current Research on Cigarette Smoking Among People with HIV. Curr Addict Rep 3, 19–26 (2016). https://doi.org/10.1007/s40429-016-0090-2

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