“ Author Information ”“
An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
In a study, a 69-year-old man was described, who developed severe infection and worsening of pre-existing COVID-19 symptoms following off-label treatment with tocilizumab for COVID-19 [route, dosage, time to reaction onsets and outcomes not stated].
Wang Y, et al. Does tocilizumab have a magical therapeutic effect on COVID-19 patients without obvious adverse reactions?. Proceedings of the National Academy of Sciences of the United States of America 117: 30896-30897, No. 49, 8 Dec 2020. Available from: URL: http://doi.org/10.1073/pnas.2009961117