COVID-19 infection: 2 case reports

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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

“ ”

In a single-center retrospective study of 170 patients with a history of orthotopic heart transplantation at Henry Ford Hospital in Detroit, Michigan, USA, 2 patients >18 years [sexes not stated; exact ages not stated] were described. The patient's developed COVID-19 infection between 13 March 2020 and 01 May 2020, following immunosuppressive treatment with ciclosporin (one patient) and triple therapy with prednisone, tacrolimus, and mycophenolate-mofetil (one patient) [dosages, routes, durations of treatments to reactions onsets and outcomes not stated].


  1. Al-Darzi W, et al. Heart transplant recipients with confirmed 2019 novel coronavirus infection: The Detroit experience. Clinical Transplantation 34: No. 12, Dec 2020. Available from: URL:

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Immunosuppressants. Reactions Weekly 1841, 127 (2021).

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