Notes
Based on data from 964 patients at Massachusetts General Hospital who received ICI therapy during the stated time period.
LVEF = left ventricular ejection fraction
CTLA-4 = cytotoxic T-lymphocyte-associated protein 4; PD-1 = programmed cell death protein 1; PD-L1 = programmed cell death ligand 1
References
Mahmood SS, et al. Myocarditis in Patients Treated With Immune Checkpoint Inhibitors. Journal of the American College of Cardiology : [10 pages], 13 Mar 2018. Available from: URL: http://dx.doi.org/10.1016/j.jacc.2018.02.037.
Tocchetti CG. Cardiac Toxicity in Patients Treated With Immune Checkpoint Inhibitors: It Is Now Time for Cardio-Immuno-Oncology. Journal of the American College of Cardiology : [3 pages], Apr 2018. Available from: URL: https://doi.org/10.1016/j.jacc.2018.02.038.
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Myocarditis after ICI therapy more common than first thought. Reactions Weekly 1697, 9 (2018). https://doi.org/10.1007/s40278-018-44565-1
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DOI: https://doi.org/10.1007/s40278-018-44565-1