Reactions Weekly

, Volume 1696, Issue 1, pp 236–236 | Cite as

Meningococcal vaccines/yellow fever vaccine

Small retinal vessel vasculopathy: case report
Case report
Author Information

An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

A 41-year-old man developed small retinal vessel vasculopathy following administration of meningococcal vaccines and yellow fever vaccine [routes and dosages not stated].

The man presented with complaint of sudden onset of a scotoma in the nasal portion of his visual field of the right eye. He reported that the scotoma as similar in size to his physiologic blind spot. The spot was constant and had not changed in size or character since onset. He described mild ocular pain with movement and retrobulbar ache in the right eye. His systems were notable for diffuse, generalized headaches for the past 2 months as well as occasional, 10 to 15 minute episodes of disequilibrium. He had been vaccinated against N. meningitides by meningococcal vaccine and yellow fever...


  1. Moysidis SN, et al. The second blind spot: Small retinal vessel vasculopathy after vaccination against Neisseria meningitidis and yellow fever. Retinal Cases and Brief Reports 11: S18-S23, Jan 2017. Available from: URL: - USACrossRefPubMedGoogle Scholar

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© Springer International Publishing AG, part of Springer Nature 2018

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