Reactions Weekly

, Volume 1695, Issue 1, pp 255–255 | Cite as


Osteoporosis and related complications: 5 case reports
Case report
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An event is serious (based on the ICH definition) when the patient outcome is:

  • * death

  • * life-threatening

  • * hospitalisation

  • * disability

  • * congenital anomaly

  • * other medically important event

In a case series, 5 patients (1 man and 4 women) were described, who developed osteoporosis and associated complications following treatment with methylprednisolone [Medrol], methylprednisolone-sodium-succinate [Solumedrol] or prednisone [routes and time to reactions onsets not stated; not all indications, dosages and outcomes stated].

Patient K.S.: A 46-year-old woman developed osteoporosis and complications like kyphosis, breathing and gastrointestinal problems related to spinal deformity, vertebral fractures L1 and 4, vertebral pain syndrome and compression of the thoracic vertebrae following treatment with prednisone. Ten years prior, she had suffered a traumatic L1 fracture. In the beginning of 2016, she was diagnosed with immunogenic hyperthyroidism with thyroid...


  1. Jensovsky J, et al. Glucocorticoid-induced osteoporosis - A medical and legal issue. Osteologicky Bulletin 22: 56-62, No. 2, 2017 [Czech; summarised from a translation] - Czech RepublicGoogle Scholar

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