Multiple drugs overdose
An event is serious (based on the ICH definition) when the patient outcome is:
* congenital anomaly
* other medically important event
This case series involved, a 29-year-old woman developed hypotension, vomiting, metabolic acidosis and acute respiratory distress syndrome following amlodipine overdose; a 19-year-old man developed metabolic acidosis, shock following atenolol and amlodipine overdose and a 17-year-old girl developed shock, pneumothorax, supraventricular tachycardia, pulseless ventricular tachycardia and multiorgan failure following propranolol, amitriptyline, fluphenazine and gabapentin overdose [not all outcomes stated].
Case 1: The 29-year-old woman was admitted to the ED with severe vomiting and hypotension 8 hours after the ingestion of 40 tablets of amlodipine 10mg (total ingested dose: 400mg). After admission, she was found oriented, conscious with BP 70/40 mmHg, respiratory...