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Antithyroid drugs linked with congenital abnormalities

  • Clinical study
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Reactions Weekly Aims and scope

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Notes

  1. Of the total cohort, 1 573 766 women delivered 1 baby and the remaining women delivered ≥2 babies.

  2. In 2009, the US FDA recommended that PTU should be reserved for women who are in their first trimester, or are allergic or intolerant to MMI. However, subsequent guidelines by professional committees advised use of PTU in the first trimester, followed by MMI thereafter.

Reference

  • Seo GH, et al. Antithyroid Drugs and Congenital Malformations: A Nationwide Korean Cohort Study. Annals of Internal Medicine : [10 pages], 23 Jan 2018. Available from: URL: http://dx.doi.org/10.7326/M17-1398

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Antithyroid drugs linked with congenital abnormalities. Reactions Weekly 1688, 8 (2018). https://doi.org/10.1007/s40278-018-41643-x

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  • DOI: https://doi.org/10.1007/s40278-018-41643-x

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