Fig. 1 | Clinical Pharmacokinetics

Fig. 1

From: Volume of Distribution is Unaffected by Metabolic Drug–Drug Interactions

Fig. 1

Box plot depictions of the absolute magnitude of change in victim drug exposure (area under the curve [AUC]) and volume of distribution at steady state (Vss) expressed as ratios of interaction to control for a all drug–drug interactions (n = 72) and b the subset of these interactions that are potentially clinically significant (with absolute AUC ratios > 1.3; n = 49). The box indicates the median and 25th and 75th percentiles, the whiskers range from minimum to maximum values, and each individual data point is also depicted

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