1 Correction to: Clin Pharmacokinet (2018) 57:1493–1528 https://doi.org/10.1007/s40262-018-0664-3

Page 1517, Section 16.1, para 1, lines 1–3 which previously read:


The pharmacokinetics of CRP was tested in small short-term studies in both healthy volunteers and in subjects with schizophrenia, with similar results [242].


Should read:


The pharmacokinetics of CRP was tested in small short-term studies in healthy volunteers [235] and also in subjects with schizophrenia [242], with similar results.


Page 1517, Section 16.1, para 1, lines 4–6 which previously read:


Cariprazine is rapidly absorbed, reaching peak concentrations between 3 and 4 h after oral dosing in healthy subjects.


Should read:


Cariprazine reached peak plasma concentrations between 3 and 4 h after oral dosing in healthy subjects.


Page 1517, Section 16.1, para 2, lines 1–5 which previously read:


Its pharmacokinetics were linear in terms of AUC but maximum concentrations were more than proportional within the dose range from 3 to 5 mg in healthy subjects. Mean half-life was 2–5 days (1.5–12.5 mg/day) in the subjects with schizophrenia [242].


Should read:


Its pharmacokinetics were linear in terms of AUC but maximum concentrations were more than proportional within the single dose range from 0.5 to 2.5 mg in healthy subjects. Mean half-life was 2–5 days (1.5–12.5 mg/day) in the subjects with schizophrenia [235].


Page 1518, Section 16.1, para 2, lines 8–11 which previously read:


Additionally, the mean concentrations of DCRP and DDCRP were approximately 30 and 40% in the patients, respectively, of CRP concentrations by the end of 12 weeks of treatment [242].


Should read:


Additionally, the mean concentrations of DCRP and DDCRP were approximately 30 and 400% in the patients, respectively, of CRP concentrations by the end of 12 weeks of treatment [242].


Page 1518, Table 8, column 1, row 2, which previously read:


Actavis 2015 [243]


Should read:


Actavis 2015 [242]


Page 1518, Table 8, column 2, row 2, which previously read:


6


Should read:


8


Page 1518, Table 8, column 6, row 3, which previously read:


32–49


Should read:


10–22.7