Dear Reader,

As we reach the final issue of Clinical Pharmacokinetics for 2017, we wish to reflect on another successful year’s achievements, and to thank all those who have contributed their time and effort to guarantee the high quality of our content.

2017 was a successful year for Clinical Pharmacokinetics. Over 110 articles have been published and, as of the end of September, 17 of these has been downloaded over 1,000 times from SpringerLink. The 10 most downloaded articles this year have been:

Weerink MAS, Struys MMRF, Hannivoort LN, Barends CRM, Absalom AR, Colin P. Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine

Shah A, Solms A, Garmann D, Katterle Y, Avramova V, Simeonov S, Lissitchkov T. Improved Pharmacokinetics with BAY 81-8973 Versus Antihemophilic Factor (Recombinant) Plasma/Albumin-Free Method: A Randomized Pharmacokinetic Study in Patients with Severe Hemophilia A

van Leeuwen RWF, Jansman FGA, Hunfeld NG, Peric R, Reyners AKL, Imholz ALT, Brouwers JRBJ, Aerts JG, van Gelder T, Mathijssen RHJ. Tyrosine Kinase Inhibitors and Proton Pump Inhibitors: An Evaluation of Treatment Options

Verheijen RB, Beijnen JH, Schellens JHM, Huitema ADR, Steeghs N. Clinical Pharmacokinetics and Pharmacodynamics of Pazopanib: Towards Optimized Dosing

Dolder PC, Schmid Y, Steuer AE, Kraemer T, Rentsch KM, Hammann F, Liechti ME. Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide in Healthy Subjects

Heise T, Stender-Petersen K, Hövelmann U, Jacobsen JB, Nosek L, Zijlstra E, Haahr H. Pharmacokinetic and Pharmacodynamic Properties of Faster-Acting Insulin Aspart versus Insulin Aspart Across a Clinically Relevant Dose Range in Subjects with Type 1 Diabetes Mellitus

Heise T, Pieber TR, Danne T, Erichsen L, Haahr H. A Pooled Analysis of Clinical Pharmacology Trials Investigating the Pharmacokinetic and Pharmacodynamic Characteristics of Fast-Acting Insulin Aspart in Adults with Type 1 Diabetes

Chen N, Zhou S, Palmisano M. Clinical Pharmacokinetics and Pharmacodynamics of Lenalidomide

Wind S, Schnell D, Ebner T, Freiwald M, Stopfer P. Clinical Pharmacokinetics and Pharmacodynamics of Afatinib

Haahr H, Fita EG, Heise T. A Review of Insulin Degludec/Insulin Aspart: Pharmacokinetic and Pharmacodynamic Properties and Their Implications in Clinical Use

The quality of articles published in the journal is also reflected in its most recent impact factor (5.216). Based in this impact factor, Clinical Pharmacokinetics is ranked 21st among 257 journals in the ‘Pharmacology & Pharmacy’ category.

Other journals in the Adis Premier Journals Portfolio (http://www.springer.com/gp/adis) continue to prosper, and this year has seen the successful launch of PharmacoEconomics - Open, the newest journal in the portfolio. The journal has published a full volume of 30 articles in its first year, plus many more online first. Following in the steps of Adis’ flagship subscription journal in the field, PharmacoEconomics, the new open-access journal focuses on cost and health outcomes associated with drugs, devices and other healthcare interventions.

We thank the authors who have contributed articles to Clinical Pharmacokinetics over the course of 2017. The skill and dedication of all authors are critical to the continued publication of the journal. The quality of published articles is also testament to the significant efforts of the peer reviewers, whose commitment ensures that the journal’s content is held to the highest possible standard. We would like to thank the following individuals who acted as reviewers for Clinical Pharmacokinetics in the last 12 months:

Leon Aarons, UK

Bassel W. Abou-Khalil, USA

Adedayo B. Adedoyin, USA

Chiara Adembri, Italy

Suresh K. Agarwal, USA

Kevin S. Akers, USA

Jan-Willem C. Alffenaar, The Netherlands

Hesham S. Al-Sallami, New Zealand

Gilberto Alves, Portugal

Matt S. Anderson, USA

Piyanan Assawasuwannakit, Thailand

Jane P. Bai, USA

Cindy Bednasz, USA

Stacey S. Berg, USA

Robert Bies, USA

Angela K. Birnbaum, USA

Marta Boffito, UK

Prithviraj Bose, USA

David W. Boulton, USA

Jordi Bover, Spain

Scott Brittain, USA

David M. Burger, The Netherlands

Howard A. Burris, USA

Elisa A.M. Calvier, The Netherlands

Dario Cattaneo, Italy

Willi Cawello, Germany

Phyllis Chan, USA

Marie-Camille Chaumais, France

Manoranjenni Chetty, UK

Catherine Chiron, France

Uwe Christians, USA

John I. Chung, USA

Pamela L. Clemens, USA

Pieter Colin, The Netherlands

Emmanuelle Comets, France

Sarah F. Cook, USA

Luis I. Cortínez, Chile

Dermot Cox, Ireland

Marie-Rose Crombag, The Netherlands

Carmen Cuffari, USA

Jessica Cusato, Italy

David Czock, Germany

Richard O. Day, Australia

Dinesh de Alwis, USA

Pieter A.J.G. De Cock, Belgium

Simona De Gregori, Italy

Mailys De Sousa Mendes, France

Brenda C.M. de Winter, The Netherlands

Xavier Delavenne, France

Fabien Despas, France

Jeroen Diepstraten, The Netherlands

Jasper Dingemanse, Switzerland

Min Dong, USA

Kevin Downes, USA

Joost P.H. Drenth, The Netherlands

Jorge Duconge, USA

Caroline Dudkowski, USA

Karel Eechoute, The Netherlands

Laure Elens, Belgium

Douglas Eleveld, The Netherlands

Nicola Ferri, Italy

Lawrence Fleckenstein, USA

Alan K. Fotoohi, Sweden

Linda G. Franken, The Netherlands

Adam Frymoyer, USA

Masahide Fudo, Japan

Javid Gaziev, Italy

Ann Gils, Belgium

Henrik Green, Sweden

Charles S. Grob, USA

Andreas H. Groll, Germany

Beatriz Guglieri-López, Spain

Howard Gurney, Australia

Manuel Haschke, Switzerland

Hazem E. Hassan, USA

Oskari Heikinheimo, Finland

Aki T. Heikkinen, Finland

Stefanie Hennig, Australia

Dennis A. Hesselink, The Netherlands

Akihiro Hisaka, Japan

Guenther Hochhaus, USA

Nicolas Hohmann, Germany

Nicholas H.G. Holford, New Zealand

Karolyn Horn, USA

Dirk Hose, Germany

Poe-Hirr Hsyu, USA

Alwin D.R. Huitema, The Netherlands

Harald Ihmsen, Germany

Arantxa Isla, Spain

Vijay Ivaturi, USA

Hiroji Iwata, Japan

Frank Jacobs, USA

Nynke Jager, The Netherlands

Abhijeet Jakate, USA

Ji-Young Jeon, Republic of Korea

Zheng Jiao, China

Marija Jovanovic, Serbia

Vincent Jullien, France

William J. Jusko, USA

Amal Kaddoumi, USA

Thomas N. Kakuda, USA

Bhargava Kandala, USA

Joshua M. Kaplan, USA

Ilias Karaiskos, Greece

Takayi Katsube, Japan

Michael B. Kays, USA

Martin G. Kees, Germany

Ron Keizer, Sweden

Frieder Keller, Germany

Tony K.L. Kiang, Canada

Tae Won Kim, Republic of Korea

Ty H. Kiser, USA

Jennifer J. Kiser, USA

Linda E. Klumpers, USA

Jill Krisl, USA

Ryuji Kubota, Japan

Hiroyi Kusuhara, Japan

Dirk R.J. Kuypers, Belgium

Luca La Colla, Italy

Bojan Lalovic, Germany

Janneke G. Langendonk, The Netherlands

Mauricio Leal, USA

Florian Lemaitre, France

Peter A. LeWitt, USA

Nicholas A. Leyland, Canada

Matthias Liechti, Switzerland

Jeffrey Lipman, Australia

Célia Lloret-Linares, France

Janel Long-Boyle, USA

Gianluigi Lunardi, Italy

Irja Lutsar, Estonia

Iftekhar Mahmood, USA

Sherif H. Mahmoud, Canada

Roberto Mandrioli, Italy

Tony Marinaki, UK

Rebecca Marsh, USA

Paul Martin, Germany

Roos Masereeuw, The Netherlands

Ron A.A. Mathot, The Netherlands

Patrick H. Maxwell, UK

Jeannine McCune, USA

Patrick McGann, USA

Rajeev Menon, USA

Sven Mensing, Germany

Dirk Jan A.R. Moes, The Netherlands

Espen Molden, Norway

Miriam Mooij, The Netherlands

Gareth Morgan, USA

Shunsuke Mori, Japan

Nele B. Mueller-Plock, Switzerland

Florin M. Musteata, USA

Thomas Nührenberg, Germany

Nisha Nanaware-Kharade, USA

Noelia Nebot, USA

Andrew Nelsen, USA

David D.P. Nicolau, USA

Jace Nielsen, USA

Valerie C. Nock, Germany

Thomas D. Nolin, USA

Kayode Ogungbenro, UK

Anne E. Olesen, Denmark

Manjunath P. Pai, USA

Amit Pai, USA

Konstantinos Papamichail, USA

Andrew Parkinson, USA

Philip N. Patsalos, UK

Charles A. Peloquin, USA

Nicolas Picard, France

Yazdi K. Pithavala, USA

Akshanth R. Polepally, USA

Marek Postula, Poland

J. Robert Powell, USA

Aurelie Premaud, France

Agnieszka Prytula, Belgium

Robert B. Raffa, USA

Barbara A. Rath, USA

Mario B. Regazzi, Italy

Joannes A.A. Reijers, The Netherlands

Margareta Reis, Sweden

George A. Ricaurte, USA

Brian I. Rini, USA

Peter J. Rix, USA

Jacques Robert, France

Jason A. Roberts, Australia

Richard A. Robson, New Zealand

Keith A. Rodvold, USA

Claire Roger, France

Annick Rousseau, France

Andrew Rowland, Australia

Frans G.M. Russel, The Netherlands

Martin Sadowski, USA

Nilanjan Saha, India

Ahmed H. Salem, USA

Ahmed M. Salem, Egypt

André J.L. Scheen, Belgium

Matthias Schwab, Germany

Abhik Sen, USA

Dhaval K. Shah, USA

Anita Shah, USA

Valentina Shakhnovich, USA

Nicolas Simon, France

Joanna Sobiak, Poland

Edoardo Spina, Italy

Christine E. Staatz, Australia

Joseph F. Standing, UK

David Stepensky, Israel

Jasper Stevens, The Netherlands

Carl-Olav Stiller, Sweden

Michel M.R.F. Struys, The Netherlands

Sherwin Sy, Brazil

Tetsuhiro Tanaka, Japan

Udaya S. Tantry, USA

Antoine Tarral, Switzerland

Hugh S. Taylor, USA

Million A. Tegenge, USA

Rob ter Heine, The Netherlands

David Ternant, France

Hoai-Thu Thai, France

Mario Thevis, Germany

Patrick Thompson, USA

Alison H. Thomson, UK

Dick Tibboel, The Netherlands

Brian Tomlinson, China

Iñaki F. Troconiz, Spain

Yasuhiro Tsuji, Japan

Nas Undre, UK

Stefan Unterecker, Germany

Françoise Van Bambeke, Belgium

Nielka van Erp, The Netherlands

Johan G.C. van Hasselt, The Netherlands

Ron H.N. van Schaik, The Netherlands

Niels Vande Casteele, USA

Alexander A. Vinks, USA

Bernard Vrijens, Belgium

Toshihiro Wajima, Japan

Jeffrey A. Wald, USA

Antje-Christine Walz, Switzerland

Gerald F. Watts, Australia

Erica Wegrzyn, USA

Eric Wenzler, USA

Paweł Wiczling, Poland

Aze Wilson, Canada

Mary Wire, USA

Jean-Baptiste Woillard, France

Bogumila Woloszcz-Gebicka, Poland

Daniel Wright, New Zealand

Yoshiaki Yamamoto, Japan

Jun Yang, USA

Wendy Yeh, USA

Markus Zeitlinger, Austria

Diansong Zhou, USA

Victoria C. Ziesenitz, Switzerland

Peying Zuo, USA

Athena F. Zuppa, USA

In addition, we would like to thank the members of the journal’s Honorary Editorial Board, who have acted as peer reviewers and authors, and have provided guidance on journal content, policy and processes:

Fatemeh Akhlaghi, Kingston, RI, USA

Karel M. Allegaert, Leuven, Belgium

Gail D. Anderson, Seattle, WA, USA

Jos H. Beijnen, Amsterdam, The Netherlands

Hans R. Brunner, Riehen, Switzerland

Etienne Chatelut, Toulouse, France

Mei-Ling Chen, Silver Spring, MD, USA

Stephen J. Clarke, Sydney, NSW, Australia

Jennifer N. Clements, Clinton, SC, USA

Marja-Liisa Dahl, Stockholm, Sweden

Neal M. Davies, Edmonton, AB, Canada

Hartmut Derendorf, Gainesville, FL, USA

C. Lindsay DeVane, Charleston, SC, USA

Saskia N. de Wildt, Nijmegen, The Netherlands

Thomas C. Dowling, Grand Rapids, MI, USA

Stephen B. Duffull, Dunedin, New Zealand

Chin B. Eap, Lausanne, Switzerland

Hirotoshi Echizen, Tokyo, Japan

Andrea N. Edginton, Waterloo, ON, Canada

Erik Eliasson, Stockholm, Sweden

Mary H.H. Ensom, Vancouver, BC, Canada

Albert Ferro, London, UK

Bruce Green, Brisbane, QLD, Australia

Saeidreza Harirforoosh, Johnson City, TN, USA

Georg Hempel, Münster, Germany

Roger W. Jelliffe, Los Angeles, CA, USA

Charlotte Kloft, Berlin, Germany

Catherine A.J. Knibbe, Nieuwegein, The Netherlands

Jörn Lötsch, Frankfurt am Main, Germany

Bernd Meibohm, Memphis, TN, USA

France Mentré, Paris, France

Gerd Mikus, Heidelberg, Germany

Gene D. Morse, Buffalo, NY, USA

Pertti J. Neuvonen, Helsinki, Finland

Federico Pea, Udine, Italy

Emilio Perucca, Pavia, Italy

Johannes H. Proost, Groningen, The Netherlands

Michael S. Roberts, Brisbane, QLD, Australia

Amparo Sánchez Navarro, Salamanca, Spain

Catherine M.T. Sherwin, Salt Lake City, UT, USA

Susan E. Tett, Brisbane, QLD, Australia

Michel Tod, Lyon, France

Daniel J. Touw,Groningen, The Netherlands

Vijay V. Upreti, San Francisco, CA, USA

John N. van den Anker, Washington, DC, USA

Teun van Gelder, Rotterdam, The Netherlands

We do hope that you have found the articles published throughout the year in Clinical Pharmacokinetics to be interesting and informative. The editorial schedule for 2018 is well under way, and we are looking forward to bringing you many high-quality and authoritative articles over the coming year.

With best wishes,

Amitabh Prakash and Anton van Rensburg

Editors, Clinical Pharmacokinetics