Electrochemical Sensors Applied for In vitro Diagnosis

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Abstract

Electrochemical sensing technology has received extensive attention from researchers for its unique detection and analysis methods as well as the promising applications in clinical diagnosis. Compared with other detection methods, such as capillary electrophoresis, high-performance liquid chromatography and liquid chromatography-tandem mass spectrometry, the electrochemical sensor overcomes the disadvantages of expensive cost and complicated operation, as an ideal device for in vitro detection. In this article, we mainly introduce some methods for the detection of biologically important compounds and cancer biomarkers, and briefly summarize the characteristics of these methods at first. And then, we also focus on the latest research progress in the application of electrochemical sensing technology to biologically important compounds’ and cancer biomarkers’ detection. Finally, the development trend and challenges of electrochemical sensing technology for in vitro diagnosis are also prospected.

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Acknowledgements

This work is partially supported by the National Natural Science Foundation of China(Nos.21605113, 21925405, 21635002 and 201874005), the National Key Research and Development Program of China(No.2018YFA0208800), and the Project of the Chinese Academy of Sciences(Nos.XDA23030106 and YJKYYQ20180044).

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  1. These authors contributed equally to this work.

Affiliations

  1. Life and Health Research Institute, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China

    Duo Li, Chao Wu, Xuehui Tang, Yue Zhang & Tie Wang

  2. Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China

    Tie Wang

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  1. Duo Li
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Li, D., Wu, C., Tang, X. et al. Electrochemical Sensors Applied for In vitro Diagnosis. Chem. Res. Chin. Univ. (2021). https://doi.org/10.1007/s40242-021-0387-0

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Keywords

  • Electrochemical sensor
  • In vitro diagnosis
  • Biologically important compound
  • Cancer biomarker