Chemical Research in Chinese Universities

, Volume 34, Issue 2, pp 260–268 | Cite as

Vc-Functionalized Fe3O4 Nanocomposites as Peroxidase-like Mimetics for H2O2 and Glucose Sensing

  • Hejun Ren
  • Taigang Ma
  • Jian Zhao
  • Rui Zhou


A simple and efficient colorimetric biosensing for hydrogen peroxide and glucose with peroxidase-like vitamin C(Vc) functionalized Fe3O4 magnetic nanoparticles(VcFe3O4 MNPs) as a catalyst is reported. Compared with Fe3O4 MNPs and other catalysts, VcFe3O4 MNPs exhibited superior catalytic properties. Kinetic studies indicated that vitamin C incorporated on Fe3O4 MNPs improved the affinity toward H2O2. As low as 0.29 μmol/L H2O2 can be detected with a wide linear range of 0.5―100 μmol/L H2O2; moreover, as low as 0.288 μmol/L glucose can be detected with a linear range of 0.5―25 μmol/L glucose. The detection method was highly sensitive in sensing H2O2 and glucose. The robustness of VcFe3O4 MNPs rendered them suitable for wide ranging applications.


VcFe3O4 Colorimetric biosensing Enzyme mimetics Hydrogen peroxide Glucose 


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Copyright information

© Jilin University, The Editorial Department of Chemical Research in Chinese Universities and Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Key Laboratory of Groundwater Resources and Environment, Ministry of Education, College of Environment and ResourcesJilin UniversityChangchunP. R. China

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