Spinal Cord Stimulation After Spinal Cord Injury: Promising Multisystem Effects


Purpose of Review

Spinal cord stimulation (SCS) is an exciting new area of research in the field of spinal cord injury (SCI) medicine. This review aims to provide an overview of recent advances in SCS related to motor control, neurogenic bladder, and cardiovascular effects and discuss future directions.

Recent Findings

Epidural spinal stimulation (spES) and transcutaneous stimulation (TSS) have been shown to improve lower and upper-extremity motor control after SCI. Similarly, SCS has shown to impact bladder function and blood pressure control after SCI. Future directions include gaining a better understanding of the associated mechanism, further optimization of stimulation parameters, coordinating the multisystem effects of SCS, and enhancing our knowledge of the benefits and limitations of spES versus TSS.


Clinicians should be aware of the growing evidence supporting the potential for multisystem effects of SCS after SCI.

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Correspondence to Jayne Donovan.

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The authors declare that they have no conflicts of interest. Dr. Linsenmeyer is a consultant for urological epidural stimulation studies at the University of Louisville, Louisville KY.

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Donovan, J., Forrest, G., Linsenmeyer, T. et al. Spinal Cord Stimulation After Spinal Cord Injury: Promising Multisystem Effects. Curr Phys Med Rehabil Rep 9, 23–31 (2021). https://doi.org/10.1007/s40141-020-00304-1

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  • Spinal cord injury
  • Spinal stimulation
  • Motor control
  • Neurogenic bladder
  • Orthostasis