Abstract
Purpose of Review
The purpose of this article is to explore the changes over the last 10 years related to limb salvage for even the most complex cases of limb trauma and describe a thoughtful approach to the mangled extremity.
Recent Findings
CT angiography has replaced formal angiography around the country with promising results for evaluating the vascular network of a limb. While concepts in skeletal fixation and vascular reconstruction have remained generally unchanged, advances in nerve grafting and conduit use will guide future directions for limb salvage and improve functional outcomes for patients.
Summary
The surgeon should consider the analogies of home building and limb salvage when planning their reconstructive steps: image review as blueprints, debridement as foundation excavation, skeletal fixation as the foundation and framework, plumbing and electric as vessel and nerve repair, and soft tissue coverage as the roof above the reconstruction.
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Salminger S, Sturma A, Roche AD, et al. Functional and psychosocial outcomes of hand transplantation compared with prosthetic fitting in below-elbow amputees: a multicenter cohort study. PLoS ONE. 2016;11(9):e0162507.
Ostlie K, Franklin RJ, Skjeldal OH, et al. Assessing physical function in adult acquired major upper-limb amputees by combining the disabilities of the arm, shoulder and hand (DASH) outcome questionnaire and clinical examination. Arch Phys Med Rehabil. 2011;92(10):1636–45.
Galanakos SP, Bot AG, Zoubos AB, et al. Psychological and social consequences after reconstruction of upper extremity trauma: methods of detection and management. J Reconstr Microsurg. 2014;30(3):193–206.
Bosse MJ, MacKenzie EJ, Kellam JF, et al. An analysis of outcomes of reconstruction or amputation after leg-threatening injuries. N Engl J Med. 2002;347(24):1924–31.
Pet MA, Morrison SD, Mack JS, et al. Comparison of patient-reported outcomes after traumatic upper extremity amputation: replantation versus prosthetic rehabilitation. Injury. 2016;47(12):2783–8.
Prasarn ML, Helfet DL, Kloen P. Management of the mangled extremity. Strateg Trauma Limb Reconstr. 2012;7(2):57–66.
Sasser S, Hunt R, Faul M, Sugerman D, Pearson W, Dulski T, et al. Guidelines for field triage of injured patients: recommendations of the national expert panel on field triage. CDC Morb Mortal Wkl Rep (MMWR). 2011;61:1–20.
Mardian S, Krapohl BD, Roffeis J, Disch AC, Schaser KD, Schwabe P. Complete major amputation of the upper extremity: early results and initial treatment algorithm. J Trauma Acute Care Surg. 2015;78(3):586–93.
Pensy, RA. The mangled extremity: chapter 1. Springer Publishing. In Press.
Peng PD, Spain DA, Tataria M, et al. CT angiography effectively evaluates extremity vascular trauma. Am Surg. 2008;74(2):103–7.
Crowley DJ, Kanakaris NK, Giannoudis PV. Irrigation of the wounds in open fractures. J Bone Joint Surg Br. 2007;89(5):580–5.
Godina M. Early microsurgical reconstruction of complex trauma of the extremities. Plasty Reconstr Surg. 1986;78(3):285–92.
FLOW Investigators, Bhandari M, Jeray KJ, Petrisor BA, et al. A trial of wound irrigation in the initial management of open fracture wounds. N Engl J Med. 2015;373(27):2629–41.
Bertol MJ, et al. Saving life and limb: limb salvage using external fixation, a multi-centre review of orthopaedic surgical activities in Médecins Sans Frontières. Int Orthop. 2014;38(8):1555–61.
Scalea TM, Boswell SA, Scott JD, Mitchell KA, Kramer ME, Pollak AN. External fixation as a bridge to intramedullary nailing for patients with multiple injuries and with femur fractures: damage control orthopedics. J Trauma. 2000;48(4):613–21 discussion 621-3.
Sagebein CA, Rodriguez ED, Turen CH. The soft tissue frame. Plast Reconstr Surg. 2007;119(7):2137–40.
Rutherford RB, Baker JD, Ernst C, et al. Recommended standards for reports dealing with lower extremity ischemia: revised version. J Vasc Surg. 1997;26(3):517–38.
Paradis S, Charles AL, Meyer A, et al. Chronology of mitochondrial and cellular events during skeletal muscle ischemia-reperfusion. Am J Physiol Cell Physiol. 2016;310(11):C968–82.
Better OS, Stein JH. Early management of shock and prophylaxis of acute renal failure in traumatic rhabdomyolysis. N Engl J Med. 1990;322(12):825–9.
deSouza IS, Benabbas R, McKee S, et al. Accuracy of physical examination, ankle-brachial index, and ultrasonography in the diagnosis of arterial injury in patients with penetrating extremity trauma: a systematic review and meta-analysis. Acad Emerg Med. 2017;24(8):994–1017.
• Nagpal P, Maller V, Garg G, et al., Upper extremity runoff: pearls and pitfalls in computed tomography angiography and magnetic resonance angiography. Curr Probl Diagn Radiol. 2017;46(2):115–129. This reference provides good evidence for the use of CTA in traumatic mangling upper extremity injuries.
Paryavi E, Pensy RA, et al. Salvage of upper extremites with humeral fracture and associated brachial artery injury. Injury. 2014;45(12):1870–5.
Gifford SM, Aidinian G, Clouse WD, et al. Effect of temporary shunting on extremity vascular injury: an outcome analysis from the Global War on Terror vascular injury initiative. J Vasc Surg. 2009;50(3):549–55.
Seddon HJ, Medawar PB, Smith H. Rate of regeneration of peripheral nerves in man. J Physiol. 1943;102:191–215.
Jabaley ME, Wallace WH, Heckler FR. Internal topography of major nerves of the forearm and hand: a current view. J Hand Surg Am. 1980;5(1):1–18.
Murovic JA. Upper extremity peripheral nerve injuries: a Louisiana State University Health Sciences Center literature review with comparison of the operative outcomes of 1837 Louisiana State University Health Sciences Center edian, radial, and ulnar nerve lesions. Neurosurgery. 2009;65(4 Suppl):A11–7.
Millesi H. Techniques for nerve grafting. Hand Clin. 2000;16(1):73–91.
•• Boeckstyns ME, Sorensen AI, Vineta JF, et al. Collagen conduit versus microsurgical neurorrhaphy: 2 year follow- up of a prospective, blinded clinical and electrophysilogical multicentered randomized, controlled. Trial. J Hand Surg Am. 2013;38(12):2405–11. This article demonstrates good clinical results of collagen conduits compared to microsurgical neurorrhaphy at 2 year follow up.
Shasti M, Jauregui JJ, Malik A, et al. Magnitude of soft-tissue defect as predictor of free flap failures: does size matter? J Orthop Trauma. 2017;31(12):e412–7.
Rasmussen TE, Tai NRM. Rich’s vascular trauma. 3rd ed. New York: Elsevier Health Sciences; 2015. p. 405.
Badash ID, Burt KA. Outcomes of soft tissue reconstruction for traumatic lower Extremity fractures with compromised vascularity. Am Surg. 2017;83(10):1161–5.
Tintle SM, Levin LS. The reconstructive microsurgery ladder in orthopaedics. Injury. 2013;44(3):376–85.
Gottlieb LJ, Krieger LM. From the reconstructive ladder to the reconstructive elevator. Plast Reconstr Surg. 1994;93(7):1503–4.
Dedmond BT, Kortesis B, Punger K, et al. The use of negative-pressure wound therapy (NPWT) in the temporary treatment of soft-tissue injuries associated with high-energy open tibial shaft fractures. J Orthop Trauma. 2007;21(1):11–7.
Bhattacharyya T, Mehta P, Smith M, et al. Routine use of wound vacuum-assisted closure does not allow coverage delay for open tibia fractures. Plast Reconstr Surg. 2008;121(4):1263–6.
Shaikh SA, Bawa A, Shahzad N, Yousufzai Z, Ghani MS. Arch Plast Surg. 2018;45(4):345–50.
Megerle K, Sauerbier M, Germann G. The evolution of the pedicled radial forearm flap. Hand. 2010;5(1):37–42.
Kelley BP, Chung KC. Soft-tissue coverage for elbow trauma. Hand Clin. 2015;31(4):693–703.
Mears SC, Zadnik MB, Eglseder WA. Salvage of functional elbow range of motion in complex open injuries using a sensate transposition lateral arm flap. Plast Reconstr Surg. 2004;113(2):531–5.
Hyakusoku H, Yamamoto T, et al. The propeller flap method. Br J Plast Surg. 1991;44:53–4.
Teo T. The propeller flap concept. Clin Plast Surg. 2010;37(4):615–26.
Khouri RK, Cooley BC, Kunselman AR, Landis JR, Yeramian P, Ingram D, Natarajan N, Benes CO, Wallemark C. A prospective study of microvascular free-flap surgery and outcome. Plast Reconstr Surg. 1998;102(3):711–21.
Masquelet AC, Gilbert A. An atlas of flaps of the musculoskeletal system. Paris: Dunitz; 2001.
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Alexander J. Kish and Raymond A. Pensy declare that they have no conflict of interest.
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Kish, A.J., Pensy, R.A. The Mangled Extremity: An Update. Curr Surg Rep 7, 6 (2019). https://doi.org/10.1007/s40137-019-0226-0
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DOI: https://doi.org/10.1007/s40137-019-0226-0