Update on Quality of Life in Glaucoma

Diagnosis and Monitoring of Glaucoma (R Kuchtey, Section Editor)
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Part of the following topical collections:
  1. Diagnosis and Monitoring of Glaucoma

Abstract

Purpose of Review

To summarize the recent studies which evaluate the relationship between quality of life and glaucoma.

Recent Findings

Vision-related quality of life (VRQOL) is a patient-reported outcome that is influenced by many factors including visual function, mental health, physical health, and education. It can be correlated to clinical measures such as visual field testing and imaging parameters. Certain thresholds of visual field loss may precede rapid loss of VRQOL. Glaucoma surgery does not decrease VRQOL and may prevent further VRQOL deterioration.

Summary

More instruments need to be developed to quickly and reliably evaluate VRQOL. In a patient-centered health care environment, a multi-faceted treatment approach is indicated for glaucoma and includes medical/surgical therapy, education, and referrals for coexisting medical conditions. In the future as the relationship between visual field and quality of life become clearer, the timing of medical and surgical interventions may change.

Keywords

Glaucoma Quality of life Visual function Patient-reported outcomes Vision-related quality of life Visual disability 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. 1.
    Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006;90:262–7.CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Goh YW, Ang GS, Azuara-Blanco A. Lifetime visual prognosis of patients with glaucoma. Clin Exp Ophthalmol. 2011;39:766–70.CrossRefPubMedGoogle Scholar
  3. 3.
    Ramulu P. Glaucoma and disability: which tasks are affected, and at what stage of disease? Curr Opin Ophthalmol. 2009;20:92–8.CrossRefPubMedPubMedCentralGoogle Scholar
  4. 4.
    Janz NK, Wren PA, Lichter PR, Musch DC, Gillespie BW, Guire KE, et al. The Collaborative Initial Glaucoma Treatment Study: interim quality of life findings after initial medical or surgical treatment of glaucoma. Ophthalmology. 2001;108:1954–65.CrossRefPubMedGoogle Scholar
  5. 5.
    •• Peters D, Heijl A, Brenner L, Bengtsson B. Visual impairment and vision-related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow-up. Acta Ophthalmol. 2015;93:745–52. Long-term results from randomized clinical trial correlating worsening visual field performance with declining VRQOL. Also identified evidence of a threshold of visual field loss where subsequent rapid VRQOL occurs. CrossRefPubMedPubMedCentralGoogle Scholar
  6. 6.
    •• Kotecha A, Feuer WJ, Barton K, Gedde SJ. Tube Versus Trabeculectomy Study Group. Quality of Life in the Tube Versus Trabeculectomy Study. Am J Ophthalmol. 2017;176:228–35. Study results from multicenter randomized clinical trial reporting on quality of life in surgically treated glaucoma patients. CrossRefPubMedGoogle Scholar
  7. 7.
    Cesareo M, Ciuffoletti E, Ricci F, Missiroli F, Giuliano MA, Mancino R, et al. Visual disability and quality of life in glaucoma patients. Prog Brain Res. 2015;221:359–74.CrossRefPubMedGoogle Scholar
  8. 8.
    Mangione CM, Lee PP, Gutierrez PR, Spritzer K, Berry S, Hays RD. Development of the 25-item National Eye Institute Visual Function Questionnaire. Arch Ophthalmol. 2001;119:1050–8.CrossRefPubMedGoogle Scholar
  9. 9.
    Che Hamzah J, Burr JM, Ramsay CR, Azuara-Blanco A, Prior M. Choosing appropriate patient-reported outcomes instrument for glaucoma research: a systematic review of vision instruments. Qual Life Res. 2011;20:1141–58.CrossRefPubMedGoogle Scholar
  10. 10.
    Dahlmann-Noor A, Tailor V, Bunce C, Abou-Rayyah Y, Adams G, Brookes J, et al. Quality of life and functional vision in children with glaucoma. Ophthalmology. 2017;124:1048–55.CrossRefPubMedGoogle Scholar
  11. 11.
    Alqudah A, Mansberger SL, Gardiner SK, Demirel S. Vision-related quality of life in glaucoma suspect or early glaucoma patients. J Glaucoma. 2016;25:629–33.CrossRefPubMedPubMedCentralGoogle Scholar
  12. 12.
    Sung KR, Chun YS, Park CK, Kim HK, Yoo C, Kim YY, et al. LIGHT (Life quality of the glaucoma patient who underwent treatment) study of Korean Glaucoma Society. Vision-related quality of life in Korean glaucoma patients. J Glaucoma. 2017;26:159–65.CrossRefPubMedGoogle Scholar
  13. 13.
    Matsuura M, Hirasawa K, Hirasawa H, Yanagisawa M, Murata H, Mayama C, et al. Developing an Item Bank to measure quality of life in individuals with glaucoma, and the results of the interview with patients: the effect of visual function, visual field progression rate, medical, and surgical treatments on quality of life. J Glaucoma. 2017;26:64–73.Google Scholar
  14. 14.
    Mogil RS, Tirsi A, Lee JM, Tello C, Park SC. Glaucoma patient-reported concerns and associated factors. Am J Ophthalmol. 2017;178:9–17.CrossRefPubMedGoogle Scholar
  15. 15.
    Altangerel U, Spaeth GL, Steinmann WC. Assessment of function related to vision (AFREV). Ophthalmic Epidemiol. 2006;13:67–80.CrossRefPubMedGoogle Scholar
  16. 16.
    Waisbourd M, Parker S, Ekici F, Martinez P, Murphy R, Scully K, et al. A prospective, longitudinal, observational cohort study examining how glaucoma affects quality of life and visually-related function over 4 years: design and methodology. BMC Ophthalmol. 2015;15:91.CrossRefPubMedPubMedCentralGoogle Scholar
  17. 17.
    Sun Y, Lin C, Waisbourd M, Ekici F, Erdem E, Wizov SS, et al. The impact of visual field clusters on performance-based measures and vision-related quality of life in patients with glaucoma. Am J Ophthalmol. 2016;163:45–52.CrossRefPubMedGoogle Scholar
  18. 18.
    Skalicky SE, McAlinden C, Khatib T, Anthony LM, Sim SY, Martin KR, et al. Activity limitation in glaucoma: objective assessment by the Cambridge Glaucoma Visual Function Test. Invest Ophthalmol Vis Sci. 2016;57:6158–66.CrossRefPubMedGoogle Scholar
  19. 19.
    Chun YS, Lee DI, Kwon J, Park IK. Comparison of impact of monocular and integrated binocular visual fields on vision-related quality of life. J Glaucoma. 2017;26:283–91.CrossRefPubMedGoogle Scholar
  20. 20.
    Okamoto M, Sugisaki K, Murata H, Hirasawa H, Mayama C, Asaoka R. Impact of better and worse eye damage on quality of life in advanced glaucoma. Sci Rep. 2014;4:4144.CrossRefPubMedPubMedCentralGoogle Scholar
  21. 21.
    Gutierrez P, Wilson MR, Johnson C, Gordon M, Cioffi GA, Ritch R, et al. Influence of glaucomatous visual field loss on health-related quality of life. Arch Ophthalmol. 1997;115:777–84.CrossRefPubMedGoogle Scholar
  22. 22.
    Sumi I, Shirato S, Matsumoto S, Araie M. The relationship between visual disability and visual field in patients with glaucoma. Ophthalmology. 2003;110:332–9.CrossRefPubMedGoogle Scholar
  23. 23.
    •• Jones L, Bryan SR, Crabb DP. Gradually then suddenly? Decline in vision-related quality of life as glaucoma worsens. J Ophthalmol. 2017;2017:1621640. Cross-sectional study that suggests that there are different phases in the relationship between visual field loss and VRQOL. CrossRefPubMedPubMedCentralGoogle Scholar
  24. 24.
    Nelson-Quigg JM, Cello K, Johnson CA. Predicting binocular visual field sensitivity from monocular visual field results. Invest Ophthalmol Vis Sci. 2000;41:2212–21.PubMedGoogle Scholar
  25. 25.
    • Cheng HC, Guo CY, Chen MJ, Ko YC, Huang N, Liu CJ. Patient-reported vision-related quality of life differences between superior and inferior hemifield visual field defects in primary open-angle glaucoma. JAMA Ophthalmol. 2015;133:269–75. A study that looks at how different areas of the visual field affect the different subsections of the NEIVFQ25. CrossRefPubMedGoogle Scholar
  26. 26.
    Abe RY, Diniz-Filho A, Costa VP, Gracitelli CP, Baig S, Medeiros FA. The impact of location of progressive visual field loss on longitudinal changes in quality of life of patients with glaucoma. Ophthalmology. 2016;123:552–7.CrossRefPubMedGoogle Scholar
  27. 27.
    •• Blumberg DM, De Moraes CG, Prager AJ, Yu Q, Al-Aswad L, Cioffi GA, et al. Association between undetected 10-2 visual field damage and vision-related quality of life in patients with glaucoma. JAMA Ophthalmol. 2017;135:742–7. A study that looks at the association of 24–2 and 10–2 visual field testing and VRQOL. CrossRefPubMedGoogle Scholar
  28. 28.
    Prager AJ, Hood DC, Liebmann JM, De Moraes CG, Al-Aswad LA, Yu Q, et al. Association of glaucoma-related, optical coherence tomography-measured macular damage with vision-related quality of life. JAMA Ophthalmol. 2017;135:783–8.CrossRefPubMedGoogle Scholar
  29. 29.
    Hirooka K, Nitta E, Ukegawa K, Tsujikawa A. Vision-related quality of life following glaucoma filtration surgery. BMC Ophthalmol. 2017;17:66.CrossRefPubMedPubMedCentralGoogle Scholar
  30. 30.
    Lim NC, Fan CH, Yong MK, Wong EP, Yip LW. Assessment of depression, anxiety, and quality of life in Singaporean patients with glaucoma. J Glaucoma. 2016;25:605–12.CrossRefPubMedGoogle Scholar
  31. 31.
    Kuo YS, Liu CJ, Cheng HC, Chen MJ, Chen WT, Ko Y. Impact of socioeconomic status on vision-related quality of life in primary open-angle glaucoma. Eye (Lond). 2017;31:1480–7.CrossRefGoogle Scholar

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Casey Eye Institute/OHSUPortlandUSA

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