Abstract
Purpose
We report on a kidney transplant recipient treated with fecal microbiota transplantation (FMT) for recurrent urinary tract infections.
Methods
FMT was administered via frozen capsulized microbiota. Before and after FMT, urinary, fecal and vaginal microbiota compositions were analyzed.
Results
The patient remained without symptoms after FMT.
Conclusions
Underlying mechanisms of action need to be addressed in depth by future research.
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References
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Acknowledgements
We thank the patient for provision of clinical data and Anastasia Tsakmaklis and Fabiola Sack for excellent laboratory support.
Funding
This work was supported by the German Research Foundation (DFG) [BI 1899/1-1].
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LMB has received lecture honoraria from Astellas and Merck/MSD, and travel grants from 3M and Gilead. MJGTV reports grants and personal fees from Astellas Pharma, Merck/MSD, Gilead Sciences, Berlin Chemie, Falk Foundation, Organobalance, Pfizer, and grants from Astellas Pharma, Merck/MSD, Seres Therapeutics, DaVolterra. All other authors: none to declare.
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Biehl, L.M., Cruz Aguilar, R., Farowski, F. et al. Fecal microbiota transplantation in a kidney transplant recipient with recurrent urinary tract infection. Infection 46, 871–874 (2018). https://doi.org/10.1007/s15010-018-1190-9
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DOI: https://doi.org/10.1007/s15010-018-1190-9