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Drug Hypersensitivity Syndrome to Carbamazepine and Human Herpes Virus 6 Infection: Case Report and Literature Review

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Abstract.

We describe a patient with a drug-induced hypersensitivity syndrome to carbamazepine and a concomitant active infection with human herpes virus 6 (HHV-6). The potential role of HHV-6 regarding the drug-induced hypersensitivity syndrome is discussed and the main clinical features of this potentially fatal adverse drug reaction are highlighted.

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Authors and Affiliations

  1. Outpatient Dept. of Internal Medicine, University Hospital Basel, Switzerland

    A. Zeller & E. Battegay

  2. Allergy Unit, Dept. of Dermatology, University Hospital Basel, Petersgraben 4, CH-4031, Basel, Switzerland

    N. Schaub & A. J. Bircher

  3. Institute for Medical Microbiology, University of Basel, Switzerland

    I. Steffen

  4. Dept. of Internal Medicine, Division of Infectious Diseases, University Hospital Basel, Switzerland

    H. H. Hirsch

Authors
  1. A. Zeller
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  2. N. Schaub
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  3. I. Steffen
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  4. E. Battegay
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  5. H. H. Hirsch
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  6. A. J. Bircher
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Corresponding author

Correspondence to A. J. Bircher.

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Zeller, A., Schaub, N., Steffen, I. et al. Drug Hypersensitivity Syndrome to Carbamazepine and Human Herpes Virus 6 Infection: Case Report and Literature Review. Infection 31, 254–256 (2003). https://doi.org/10.1007/s15010-002-3099-5

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  • DOI: https://doi.org/10.1007/s15010-002-3099-5

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