AKUPUNKTUR VERBESSERT DIE NEBENWIRKUNGEN VON ANTIHORMONELLEN THERAPIEN BEIM BRUSTKREBS

ACUPUNCTURE IMPROVES SIDE EFFECTS FROM ANTIHORMONAL THERAPIES IN BREAST CANCER

Zusammenfassung

Ziel der Studie war es, den Effekt der Akupunktur bei Mammakarzinom-Patientinnen mit laufender antihormoneller Therapie zu untersuchen. In die Studie wurden 25 Patientinnen inkludiert, welche im Jahr 2014 an der Abteilung für Komplementärmedizin Krankenhaus F. Tappeiner Meran (Italien) während der antihormonellen Therapie Akupunkturbehandlungen erhalten haben. Unsere Daten zeigen, dass nach Beendigung der Therapie 96,15 % der Patienten eine Verbesserung der Nebenwirkungen der antihormonellen Therapie durch die Akupunktur in Hinblick auf Hitzewallungen, Gelenksschmerzen, Schlafstörungen, Stimmungsschwankungen und Schweißausbrüche verspürten (p < 0,001). Besonders die Gelenkschmerzen, welche vor allem eine Nebenwirkung in den ersten Therapiemonaten von Aromataseinhibitoren sind, konnten bei einem Großteil der Patientinnen um mehr als 50 % verbessert werden. Zusammenfassend erweitert die vorliegende Studie die aktuelle Datenlage zur additiven Akupunkturbehandlung beim Mammakarzinom und zeigt den positiven Effekt der Akupunktur auf unerwünschte Nebenwirkungen der antihormoneller Therapie beim Mammakarzinom.

Summary

The aim of the study was to investigate the effect of acupuncture in breast cancer patients with ongoing antihormonal therapy. 25 patients who received acupuncture treatments in 2014 at the Department of Complementary Medicine Hospital F. Tappeiner Merano (Italy) during antihormonal therapy were included in this prospective study.

Our data show that after completion of therapy 96.15 % of patients observed an improvement of side effects of antihormonal therapy through acupuncture regarding hot flashes, joint pain, sleep problems, mood swings and sweats (p < 0.001). In particular, joint pain, which is a predominant side effect during the first months of therapy with aromatase inhibitors, was improved more than 50 % in a majority of patients.

In summary, this study expands the current data for additive acupuncture treatment for breast cancer and shows the positive effect of acupuncture on side effects of hormone therapy in breast cancer.

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Literatur

  1. [1]

    Dobos G, Tao I: The model of Western integrative medicine: the role of Chinese medicine. Chin J Integr Med. 2011 Jan; 17(1):11–20.

    Article  Google Scholar 

  2. [2]

    Garcia MK, McQuade J, Haddad R, Patel S, Lee R, Yang P, Palmer JL, Cohen L.J: Systematic review of acupuncture in cancer care: a synthesis of the evidence. Clin Oncol. 2013 Mar 1;31(7):952–60.

    Article  Google Scholar 

  3. [3]

    Molassiotis A, Bardy J, Finnegan-John J, Mackereth P, Ryder DW, Filshie J, Ream E, Richardson A: Acupuncture for cancerrelated fatigue in patients with breast cancer: a pragmatic randomized controlled trial. J Clin Oncol. 2012 Dec 20; 30(36):4470–629.

    Article  Google Scholar 

  4. [4]

    Crew K D, Capodice JL, Greenlee H, Brafman L, Fuentes D, Awad D, Yann Tsai W, Hershman DL: Randomized, blinded, sham-controlled trial of acupuncture for the management of aromatase inhibitor-associated joint symptoms in women with early-stage breast cancer. J Clin Oncol. 2010 Mar 1; 28(7):1154–60.

    CAS  Article  Google Scholar 

  5. [5]

    Bao T, Cai L, Giles JT et al: A dual-center randomized controlled double blind trial assessing the effect of acupuncture in reducing musculoskeletal symptoms in breast cancer patients taking aromatase inhibitors. Breast Cancer Res Treat 2013; 138: 167–174.

    CAS  Article  Google Scholar 

  6. [6]

    Bokmand S, Flyger H: Acupuncture relieves menopausal discomfort in breast cancer patients: a prospective, double blinded, randomized study. Breast. 2013 Jun;22(3):320–3.

    Article  Google Scholar 

  7. [7]

    Deng G, Vickers A, Yeung S, D’Andrea GM, Xiao H, Heerdt AS, Sugarman S, Troso-Sandoval T, Seidman AD, Hudis CA, Cassileth B.: Randomized, controlled trial of acupuncture for the treatment of hot flashes in breast cancer patients. J Clin Oncol. 2007 Dec 10; 25(35):5584–90.

    Article  Google Scholar 

  8. [8]

    Hervik J, Mjåland O: Acupuncture for the treatment of hot flashes in breast cancer patients, a randomized, controlled trial. Breast Cancer Res Treat. 2009 Jul;116(2):311.

    Article  Google Scholar 

  9. [9]

    Lee MS, Kim KH, Choi SM, Ernst E: Acupuncture for treating hot flashes in breast cancer patients: a systematic review. Breast Cancer Res Treat. 2009 Jun;115(3):497–503.

    Article  Google Scholar 

  10. [10]

    Walker EM, Rodriguez AI, Kohn B, Ball RM, Pegg J, Pocock JR, Nunez R, Peterson E, Jakary S, Levine RA.: Acupuncture versus venlafaxine for the management of vasomotor symptoms in patients with hormone receptor-positive breast cancer: a randomized controlled trial. J Clin Oncol. 2010 Feb 1;28(4):634–40.

    CAS  Article  Google Scholar 

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Correspondence to Dr. med. univ. Hildegard Zeisel.

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Zeisel, H., Heidegger, H. & Thuile, C. AKUPUNKTUR VERBESSERT DIE NEBENWIRKUNGEN VON ANTIHORMONELLEN THERAPIEN BEIM BRUSTKREBS. Akupunkt Aurikulomed 41, 16–20 (2015). https://doi.org/10.1007/s15009-015-5359-3

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Schlüsselwörter

  • Mammakarzinom
  • antihormonelle Therapie
  • Akupunktur
  • Nebenwirkungen

Keywords

  • Breast cancer
  • antihormonal treatment
  • acupuncture
  • side effects