Mangels kontrollierter Studien herrscht bezüglich des perioperativen Umgangs mit Immunsuppressiva große Unsicherheit. Das gilt auch für operative Eingriffe an Gelenken. Weitertherapie ohne Pause kann das postoperative Risiko für Infektionen und Wundheilungsstörungen erhöhen, zu langes Pausieren einen Schub der Grunderkrankung auslösen. Faktoren wie Aktivität der Grunderkrankung, Komorbiditäten, individuelle Infektanamnese und Art des Eingriffes modulieren das Risiko zusätzlich.
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Krüger, K. Perioperatives Management bei Gelenkeingriffen unter Immunsuppressiva. Orthop. Rheuma 21, 39–43 (2018). https://doi.org/10.1007/s15002-018-1334-4
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DOI: https://doi.org/10.1007/s15002-018-1334-4