Biomaterials for the Treatment of Tendon Injury
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Most tendon injuries are occurring from a gradual wearing and tearing of the tendon tissues from overuse. Such injuries are usually seen in sports, exercising, or daily activities that involve a high mechanical load and weight bearing. However, owing to the lack of both cellularity and blood vessels in tendons, the process of tendon repair is slow and inefficient. Although various conservative (non-surgical) and surgical management options are conducted by the clinicians, a gold standard of these approaches does not exist. In this regard, the treatment of tendon injuries is challenging.
Here, we describe the recent advances of biomaterial-based approaches for the treatment of injured tendons.
Regenerative medicine is an emerging multidisciplinary research that specializes in the repair of damaged tendon tissues through the delivery of regenerative factors by biomaterials.
Although current biomaterial-based treatment strategies have shown their potential for tendon healing, future research and clinical applications should focused on finding the optimum combinations of regenerative factors with ideal biomaterials for the repair of tendons.
KeywordsTendon healing Delivery Biomaterials Regenerative factor Blood vessel
This research was supported by The Bio & Medical Technology Development Program of the NRF funded by the Korean government, MSIP (NRF-2017M3A9F5030273) and by a Korea University Grant (K1710531).
Conflict of interest
The authors declare that they have no conflict of interest.
There were no animal experiments carried out for this article.
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