Journal of the Iranian Chemical Society

, Volume 15, Issue 7, pp 1467–1475 | Cite as

Enhanced antibacterial activity of functionalized graphene by azo-pyridinium compounds

  • Sakineh Omidi
  • Ali Kakanejadifard
  • Farideh Azarbani
Original Paper

Abstract

For enhancement of antibacterial properties, two azo compounds were grafted on the aminated graphene by using the imine linkage. The azo compounds included pyridinium unit with different alkyl long chains. The new nanohybrids were characterized by Fourier transform infrared spectra, X-ray powder diffraction, ultraviolet–visible, field emission scanning electron microscopy (FE-SEM), atomic force microscopy, zeta potential, and energy-dispersive X-ray spectroscopy. The hybrids were investigated for antibacterial effect against Staphylococcus aureus and Escherichia coli as models of Gram-positive and Gram-negative bacteria. The nanohybrids showed a significant effect on both bacteria. Destruction of the cell wall and discharge of intracellular contents could be detected from FE-SEM images of bacteria after exposed to nanohybrids. The nanohybrid with C10 alkyl chain in the pyridinium unit displayed the highest antibacterial activity.

Graphical Abstract

Antibacterial activity of graphene–azo nanocomposite against E. coli and S. aureus was enhanced. Destruction of the cell wall and shrinking of bacteria are observed in FE-SEM image.

Keywords

Antibacterial activity Graphene Imine linkage Pyridinium salt 

Notes

Acknowledgements

We are grateful to the Lorestan University for financial support of this work.

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Copyright information

© Iranian Chemical Society 2018

Authors and Affiliations

  • Sakineh Omidi
    • 1
  • Ali Kakanejadifard
    • 1
  • Farideh Azarbani
    • 2
  1. 1.Department of ChemistryLorestan UniversityKhorramabadIran
  2. 2.Department of BiologyLorestan UniversityKhorramabadIran

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