CEN Case Reports

, Volume 7, Issue 1, pp 187–188 | Cite as

Chronic nephritis associated with X-linked thrombocytopenia

  • Tadashi YoshidaEmail author
  • Osamu Yamazaki
  • Matsuhiko Hayashi
Letter to the Editor


Compliance with ethical standards

Conflict of interest

The authors have declared that no conflict of interest exists.

Human and animal rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee at which the studies were conducted (IRB Approval Number 20130388) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from an individual participant included in the study.


  1. 1.
    Imai K, Morio T, Zhu Y, Jin Y, Itoh S, Kajiwara M, Yata J, Mizutani S. Clinical course of patients with WASP gene mutations. Blood. 2004;103:456–64.CrossRefPubMedGoogle Scholar
  2. 2.
    Albert MH, Bittner TC, Nonoyama S, Notarangelo LD, Burns S, Imai K, Espanol T, Fasth A, Pellier I, Strauss G, Morio T, Gathmann B, Noordzij JG, Fillat C, Hoenig M, Nathrath M, Meindl A, Pagel P, Wintergerst U, Fischer A, Thrasher AJ, Belohradsky BH, Ochs HD. X-linked thrombocytopenia (XLT) due to WAS mutations: clinical characteristics, long-term outcome, and treatment options. Blood. 2010;115:3231–8.CrossRefPubMedGoogle Scholar
  3. 3.
    Fried S, Matalon O, Noy E, Barda-Saad M. WIP: more than a WASp-interacting protein. J Leukoc Biol. 2014;96:713–27.CrossRefPubMedGoogle Scholar
  4. 4.
    Hattori S, Kanda S, Harita Y. Tyrosine kinase signaling in kidney glomerular podocytes. J Signal Transduct. 2011; 2011:317852.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Oshima K, Imai K, Albert MH, Bittner TC, Strauss G, Filipovich AH, Morio T, Kapoor N, Dalal J, Schultz KR, Casper JT, Notarangelo LD, Ochs HD, Nonoyama S. Hematopoietic stem cell transplantation for X-linked thrombocytopenia with mutations in the WAS gene. J Clin Immunol. 2015;35:15–21.CrossRefPubMedGoogle Scholar

Copyright information

© Japanese Society of Nephrology 2018

Authors and Affiliations

  • Tadashi Yoshida
    • 1
    • 2
    Email author
  • Osamu Yamazaki
    • 1
    • 2
  • Matsuhiko Hayashi
    • 1
    • 2
  1. 1.Apheresis and Dialysis Center, School of MedicineKeio UniversityTokyoJapan
  2. 2.Department of General Medicine, School of MedicineKeio UniversityTokyoJapan

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