Immunoprofilo nei pazienti affetti da psoriasi

  • Elio Gulletta
  • Valerio Mazzei
  • Antonella Magliocchi
  • Maria Concetta Berlinghieri
L’Osservatorio
  • 7 Downloads

Immunoprofile in psoriatic patients

Summary

The most recent literature’s evidences on pathogenic mechanisms of psoriasis have been presented. They involve genetic factors, immune-response alteration, cytokines hyper-production and can be triggered by environmental stress. Thus, psoriasis may evolve in different and subsequent phases with different clinical behavior. The laboratory can support the early diagnosis and may address a personalized therapeutic treatment performing the evaluation of the immunoprofile of the patient. This consists in the measurement of the number and the activity of lymphocytes involved in this disease, for instance T-reg, and in the evaluation of circulating levels of cytokines, for instance IL-1, IL-17, TNF\(\alpha \), through accurate and reproducible methodologies in order to perform a correct diagnosis and evaluate the efficacy of the personalized therapy.

Keywords

Citokines Immunoprofile Psoriasis 

Notes

Conflitti di interesse

Nessuno.

Studi condotti su esseri umani e animali

Non applicabile.

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Copyright information

© Società Italiana di Patologia Clinica e Medicina di Laboratorio 2018

Authors and Affiliations

  1. 1.Patologia clinica, Università Magna GraeciaAOU Mater DominiCatanzaroItalia

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