Immunoprofilo nei pazienti affetti da psoriasi

  • Elio Gulletta
  • Valerio Mazzei
  • Antonella Magliocchi
  • Maria Concetta Berlinghieri

Immunoprofile in psoriatic patients


The most recent literature’s evidences on pathogenic mechanisms of psoriasis have been presented. They involve genetic factors, immune-response alteration, cytokines hyper-production and can be triggered by environmental stress. Thus, psoriasis may evolve in different and subsequent phases with different clinical behavior. The laboratory can support the early diagnosis and may address a personalized therapeutic treatment performing the evaluation of the immunoprofile of the patient. This consists in the measurement of the number and the activity of lymphocytes involved in this disease, for instance T-reg, and in the evaluation of circulating levels of cytokines, for instance IL-1, IL-17, TNF\(\alpha \), through accurate and reproducible methodologies in order to perform a correct diagnosis and evaluate the efficacy of the personalized therapy.


Citokines Immunoprofile Psoriasis 


Conflitti di interesse


Studi condotti su esseri umani e animali

Non applicabile.


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Copyright information

© Società Italiana di Patologia Clinica e Medicina di Laboratorio 2018

Authors and Affiliations

  1. 1.Patologia clinica, Università Magna GraeciaAOU Mater DominiCatanzaroItalia

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