Résumé
L’impact de l’utilisation d’une technique d’épuration extrarénale (EER) continue ou intermittente en termes de survie, de récupération de la fonction rénale et de tolérance hémodynamique n’est pas établi, y compris chez les patients en défaillance multiviscérale dans un contexte de sepsis. Les objectifs de l’EER en réanimation sont la correction des désordres hydroélectrolytiques, la clairance de l’urée et le contrôle de la balance hydrique. Ces objectifs doivent s’adapter aux besoins du patient. La tolérance hémodynamique est primordiale pour assurer ces objectifs. Des réglages adaptés permettent l’utilisation de l’hémodialyse intermittente, même chez les patients les plus instables.
Abstract
The best choice of renal replacement therapy technique remains debated in critically ill patients. There is no evidence that this choice impacts on survival, adverse events or renal recovery. The objectives of renal replacement therapy are the correction of metabolic disturbances, the prevention of uremic syndrome and the management fluid balance. These objectives should fit to patient’s needs. Hemodynamic tolerance must be optimized to reach these objectives. If adequate settings are selected, intermittent hemodialysis can be safely applied even in the most severe septic patients.
Références
Schortgen F, Soubrier N, Delclaux C, Thuong M, Girou E, Brun-Buisson C, Lemaire F, Brochard L, (2000) Hemodynamic tolerance of intermittent hemodialysis in critically ill patients: usefulness of practice guidelines. Am J Respir Crit Care Med 162: 197–202
Vinsonneau C, Allain-Launay E, Blayau C, Darmon M, Ducheyron D, Gaillot T, Honore PM, Javouhey E, Krummel T, Lahoche A, Letacon S, Legrand M, Monchi M, Ridel C, Robert R, Schortgen F, Souweine B, Vaillant P, Velly L, Osman D, Van Vong L, (2015) Renal replacement therapy in adult and pediatric intensive care: recommendations by an expert panel from the French Intensive Care Society (SRLF) with the French Society of Anesthesia Intensive Care (Sfar) French Group for Pediatric Intensive Care Emergencies (GFRUP) the French Dialysis Society (SFD). Ann Intensive Care 5: 1–19
Acute Kidney Injury Work Group, (2012) Improving Global Outcomes (KDIGO), KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Inter 2: 89–115
Gaudry S, Hajage D, Schortgen F, Martin-Lefevre L, Pons B, Boulet E, Boyer A, Chevrel G, Lerolle N, Carpentier D, de Prost N, Lautrette A, Bretagnol A, Mayaux J, Nseir S, Megarbane B, Thirion M, Forel JM, Maizel J, Yonis H, Markowicz P, Thiery G, Tubach F, Ricard JD, Dreyfuss D, Group AS, (2016) Initiation strategies for renal replacement therapy in the intensive care unit. N Engl J Med 375: 122–133
Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, de Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP, (2017) Surviving sepsis campaign: International Guidelines for management of sepsis and septic shock: 2016. Intensive Care Med 43: 304–377
Wiedemann HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, de Boisblanc B, Connors AF Jr, Hite RD, Harabin AL, (2006) Comparison of two fluid-management strategies in acute lung injury. N Engl J Med 354: 2564–2575
Murphy CV, Schramm GE, Doherty JA, Reichley RM, Gajic O, Afessa B, Micek ST, Kollef MH, (2009) The importance of fluid management in acute lung injury secondary to septic shock. Chest 24: 24
Vinsonneau C, Camus C, Combes A, Costa de Beauregard MA, Klouche K, Boulain T, Pallot JL, Chiche JD, Taupin P, Landais P, Dhainaut JF, (2006) Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial. Lancet 368: 379–385
Zarbock A, Kellum JA, Schmidt C, Van Aken H, Wempe C, Pavenstadt H, Boanta A, Gerss J, Meersch M, (2016) Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: the ELAIN Randomized Clinical Trial. JAMA 315: 2190–2199
Vaara ST, Korhonen AM, Kaukonen KM, Nisula S, Inkinen O, Hoppu S, Laurila JJ, Mildh L, Reinikainen M, Lund V, Parviainen I, Pettila V, (2012) Fluid overload is associated with an increased risk for 90-day mortality in critically ill patients with renal replacement therapy: data from the prospective FINNAKI study. Crit Care 16: 2–11
Upadya A, Tilluckdharry L, Muralidharan V, Amoateng-Adjepong Y, Manthous CA, (2005) Fluid balance and weaning outcomes. Intensive Care Med 31: 1643–1647
Schiffl H, Lang SM, Fischer R, (2002) Daily hemodialysis and the outcome of acute renal failure. N Engl J Med 346: 305–310
Monnet X, Cipriani F, Camous L, Sentenac P, Dres M, Krastinova E, Anguel N, Richard C, Teboul JL, (2016) The passive leg raising test to guide fluid removal in critically ill patients. Ann Intensive Care 6: 46
Palevsky PM, Zhang JH, O’Connor TZ, Chertow GM, Crowley ST, Choudhury D, Finkel K, Kellum JA, Paganini E, Schein RM, Smith MW, Swanson KM, Thompson BT, Vijayan A, Watnick S, Star RA, Peduzzi P, (2008) Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 359: 7–20
Demirjian S, Teo BW, Guzman JA, Heyka RJ, Paganini EP, Fissell WH, Schold JD, Schreiber MJ, (2011) Hypophosphatemia during continuous hemodialysis is associated with prolonged respiratory failure in patients with acute kidney injury. Nephrol Dial Transplant 26: 3508–3514
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Commereuc, M., Schortgen, F. Défaillance rénale au cours du sepsis : quand et comment je débute l’EER ?. Méd. Intensive Réa 26, 449–455 (2017). https://doi.org/10.1007/s13546-017-1307-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13546-017-1307-7