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Detoxification of gold surfaces by OH• treatment

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Abstract

Metallic gold is not completely inert towards biological tissues and cells. Cytotoxicity and immunotoxicity are concerns in various gold applications. This study shows that treating the surface of gold with OH• radicals renders the gold surface non-cytotoxic, as well as prevents any biocorrosion of gold implants by an immune reaction. The detoxification is discussed as resulting from the selective dissolution of active gold atoms from the surface.

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Acknowledgements

Unfortunately, we cannot retrace the current addresses of Solveigh Krusekopf and Bich Thu Tran, whom we regard as co-authors, but because the journal does not accept co-authors without addresses, we have to acknowledge their contribution in that way.

Funding

The authors acknowledge kind support by the European Social Fund and the European Regional Development Fund. K. Vahl and B. T. Tran were supported by a fellowship of the Alfried Krupp Wissenschaftskolleg Greifswald.

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Authors and Affiliations

  1. Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17489, Greifswald, Germany

    Katja Vahl, Tyll Utesch, Ulrich Hasse, Heike Kahlert & Fritz Scholz

  2. Institute of Immunology and Transfusion Medicine, University of Greifswald, Ferdinand-Sauerbruch-Str. DZ7, 17487, Greifswald, Germany

    Robert S. Jack

  3. GILUPI GmbH, Hermannswerder 20a, 14473, Potsdam, Germany

    Andreas Bollmann & Klaus Lücke

Authors
  1. Katja Vahl
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  2. Tyll Utesch
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  3. Ulrich Hasse
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  4. Heike Kahlert
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  5. Robert S. Jack
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  6. Andreas Bollmann
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  7. Klaus Lücke
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  8. Fritz Scholz
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Correspondence to Heike Kahlert.

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Vahl, K., Utesch, T., Hasse, U. et al. Detoxification of gold surfaces by OH• treatment. Gold Bull 52, 99–103 (2019). https://doi.org/10.1007/s13404-019-00257-x

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  • DOI: https://doi.org/10.1007/s13404-019-00257-x

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