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Neuroschistosomiasis: An Unusual Intracranial Space Occupying Lesion

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Abstract

Background

Neuroschistosomiasis is an uncommonly reported disease.

Case characteristics

An adolescent Indian boy residing in Kenya presented with headache, visual symptoms and seizures, with MRI showing space-occupying lesions in the occipital lobe and cerebellum.

Observation

Brain biopsy was diagnostic of neuro-schistosomiasis; complete recovery was seen with praziquantel and corticosteroid therapy.

Message

This case highlights the importance of considering epidemiology in differential diagnosis and establishing definitive diagnosis even if it is by invasive methods.

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References

  1. Gryseels B, Polman K, Clerinx J, Kestens L. Human schistosomiasis. Lancet. 2006; 368: 1106–18.

    Article  PubMed  Google Scholar 

  2. WHO fact sheet updated January 2017. Available from: http://www.who.int/en/news-room/fact-sheets/detail/schistosomiasis. Accessed June 12, 2017.

  3. Kali A. Schistosome infections: An Indian perspective. J Clin Diagn Res. 2015;9:DE01–4.

    CAS  PubMed  PubMed Central  Google Scholar 

  4. Ferrari TC, Moreira PR. Neuroschistosomiasis: Clinical symptoms and pathogenesis. Lancet Neurol. 2011;10: 853–64.

    Article  PubMed  Google Scholar 

  5. Imai K, Koibuchi T, Kumagai T, Maeda T, Osada Y, Ohta N, et al. Cerebral schistosomiasis due to Schistosoma haematobium confirmed by PCR analysis of brain specimen. J Clin Microbiol. 2011;49:3703–6.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Pollner JH, Schwartz A, Kobrine A, Parenti DM. Cerebral schistosomiasis caused by Schistosoma haematobium: Case Report. Clin Infect Dis. 1994;18:354–7.

    Article  CAS  PubMed  Google Scholar 

  7. Alves W. The distribution of schistosoma eggs in human tissues. Bull World Health Organ. 1958;18:1092–97.

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Liu H, Lim CC, Feng X, Yao Z, Chen Y, Sun H, et al. MRI in cerebral schistosomiasis: Characteristic nodular enhancement in 33 patients. Am J Roentgenol. 2008;191:582–8.

    Article  Google Scholar 

  9. Härter G, Frickmann H, Zenk S, Wichmann D, Ammann B, Kern P, et al. Diagnosis of neuroschistosomiasis by antibody specificity index and semi-quantitative real-time PCR from cerebrospinal fluid and serum. J Med Microbiol. 2014;63:309–12.

    Article  PubMed  Google Scholar 

  10. Zhu F, Huang X, Wu M, Jin WX, Xie K. Diagnosis and treatment of cerebral schistosomiasis: A report of 166 cases. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2014;26: 695–6.

    PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Departments of Laboratory Medicine, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, India

    Nevitha Athikari Manamal

  2. Departments of Pediatrics, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, India

    Tanu Singhal

  3. Departments of Neurosurgery, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, India

    Abhaya Kumar

  4. Departments of Radiology, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, India

    Darshana Sanghvi

  5. Departments of Neurology, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, India

    Jayanti Mani

Authors
  1. Nevitha Athikari Manamal
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  2. Tanu Singhal
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  3. Abhaya Kumar
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  4. Darshana Sanghvi
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  5. Jayanti Mani
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Corresponding author

Correspondence to Tanu Singhal.

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Cite this article

Manamal, N.A., Singhal, T., Kumar, A. et al. Neuroschistosomiasis: An Unusual Intracranial Space Occupying Lesion. Indian Pediatr 55, 993–994 (2018). https://doi.org/10.1007/s13312-018-1425-y

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  • DOI: https://doi.org/10.1007/s13312-018-1425-y

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