Role of Hyperbaric Medicine for Osteoradionecrosis and Post Irradiation Wounds: an Institutional Experience

Abstract

To study the effectiveness of hyperbaric medicine in osteoradionecrosis and irradiation induced wounds. To evolve a protocol for management with combined surgical modality for irradiation induced injury. This study was carried out in the Plastic Surgery Department, from November 2011 to December 2018. A total of 30 patients with post irradiation patients subjected to hyperbaric oxygen therapy during the management were enrolled in the study. The results regarding the changes in wound and complications were noted. Out of 30 patients, 20 patients were with radiation injury involving the oral cavity, one patient with left lower limb, one with breast, 3 with radiation injury of cheek, 3 of mandible, one with radiation cystitis and one involving the tooth socket. One patient experienced reversible myopia as a complication of hyperbaric therapy. No other complications were noted. Hyperbaric therapy is a useful adjunct for surgery in management of osteoradionecrosis and post irradiation wound and proves therapeutic in some post irradiated wound where we cannot offer surgical correction.

This is a preview of subscription content, log in to check access.

Fig. 1
Fig. 2
Fig. 3

References

  1. 1.

    Gesell L, editor. Hyperbaric oxygen 2008: indications and results. The Hyperbaric Oxygen Therapy Committee Report. Durham, NC: Undersea and Hyperbaric Medical Society; 2008

  2. 2.

    Craighead P, Shea-Budgell MA, Nation J et al (2011) Hyperbaric oxygen therapy for late radiation tissue injury in gynecologic malignancies. Curr Oncol 18(5):220–227

    CAS  Article  Google Scholar 

  3. 3.

    Niinikoski JHA (2004) Clinical hyperbaric oxygen therapy, wound perfusion and transcutaneous oximetry. World J Surg 28:307–311

    Article  Google Scholar 

  4. 4.

    Tandara A, Mustoe TA (2004) Oxygen in wound healing –more than a nutrient. World J Surg 28:294–300

    Article  Google Scholar 

  5. 5.

    Yan L, Liang T, Cheng O (2015) Hyperbaric oxygen therapy in China. Medical Gas Research 5:1–3

    Article  Google Scholar 

  6. 6.

    Prada FS, Arrunategui G, Alves MC, Ferreira MC, Zumiotti AV (2002) Effect of allopurinol, superoxide-dismutase, and hyperbaric oxygen on flap survival. Microsurgery 22:352–360

    Article  Google Scholar 

  7. 7.

    Hammarlund C, Sundberg T (1994) Hyperbaric oxygen reduced size of chronic leg ulcers:a randomized double-blind study. Plast Reconstr Surg 93:829–833

    CAS  Article  Google Scholar 

  8. 8.

    Niinikoski J, Hunt TK (1996) Oxygen and healing wounds: tissue-bone repair enhancement. Handbook of Hyperbaric Medicine:485–597

  9. 9.

    Niinikoski J, Hunt TK, Dunphy JE (1972) Oxygen supply in healing tissue. Am J Surg 123:247–252

    CAS  Article  Google Scholar 

  10. 10.

    Sahni T, Singh P, John MJ (2003) Hyperbaric oxygen therapy: current trends and applications. Journal-association of physicians of india 51:280–288

    CAS  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Pradeoth Mukundan Korambayil.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Korambayil, P.M., Ambookan, P.V., Pillai, S. et al. Role of Hyperbaric Medicine for Osteoradionecrosis and Post Irradiation Wounds: an Institutional Experience. Indian J Surg Oncol (2020). https://doi.org/10.1007/s13193-020-01128-0

Download citation

Keywords

  • Hyperbaric medicine
  • Osteoradionecrosis
  • Post irradiation wounds