Abstract
Aim
To present our experience of surgical management of Crohn’s disease, incidentally found during laparotomy performed for appendicitis, and also to review the literature.
Patients — methods
Between January 2009 and January 2010, a total of 49 patients underwent laparotomy following a preoperative clinical diagnosis of acute appendicitis, of whom 17 were female and 32 male, with ages ranging from 25 to 64 years (mean age 27 years). Three of these patients, two males aged 32 and 17 years and one female 35 years, presented with severe inflammation, stenosis and oedema of the terminal ileum and mesentery of the ileocaecal area. The female patient also displayed a fistula between the terminal ileum and sigmoid colon as well as two other lesions in the small intestine. All patients were subjected to an ileocaecal resection and side-to-side ileo-ascending colon anastomosis. The female patient underwent repair of the fistula on the sigmoid colon; further intervention for the two other lesions was unnecessary since the stenosis was not considered severe.
Results
Histopathologic examination confirmed the diagnosis of Crohn’s disease. No postoperative complications were observed and the patients were subsequently referred to the gastroenterologist.
Conclusion
In Crohn’s disease found at laparotomy for appendicitis, an ileocaecal resection is recommended. The follow-up and therapy of these patients is undertaken by the gastroenterologist.
Similar content being viewed by others
References
Goldberg PA, Wright JP, Gerber M, Claassen R. Incidence of surgical resection for Crohn’s disease. Dis Colon Rectum 1993;36:736–739
Weston LA, Roberts PL, Schoetz DJ, Coller JA, Murray JJ, Rusin LC. Ileocolic resection for acute presentation of Crohn’s disease of the ileum. Dis Colon Rectum 1996;39:841–846
Crohn BB, Ginzburg L, Oppenheimer GD. Regional ileitis: a pathologic and clinical entity. JAMA 1932;99:1323–1329
Crohn BB. The pathology of acute regional ileitis Am J Dig Dis 1965;10:565–572
Baba S. Surgical treatment for Crohn’s disease. Nippon Geka Gakkai Zasshi. 1997;98:424–430
Post S, Herfarth C, Böhm E, Timmermanns G, Schumacher H, Schürmann G, Golling M. The impact of disease pattern, surgical management, and individual surgeons on the risk for relaparotomy for recurrent Crohn’s disease. Ann Surg. 1996;223:253–260.
Krupnick AS, Morris JB. The long-term results of resection and multiple resections in Crohn’s disease. Semin Gastrointest Dis. 2000;11:41–51
Mekhjian HS, Switz DM, Watts HD, Deren JJ, Katon RM, Beman FM. National Cooperative Crohn’s Disease Study: factors determining recurrence of Crohn’s disease after surgery. Gastroenterology. 1979;77:907–913
Canin-Endres J, Salky B, Gattorno F, Edye M. Laparoscopically assisted intestinal resection in 88 patients with Crohn’s disease. Surg Endosc. 1999;13:595–599
Alexander - Williams J. The technique of intestinal strictureplasty. Int J Colorectal Dis 1986;1:54–57
Hultén L. Surgical management and strategy in classical Crohn’s disease. Int Surg 1992;77:2–8
Scott NA, Hughes LE. Timing of ileocolic resection for symptomatic Crohn’s disease — the patient’s view. Gut 1994; 35; 656–657
Yazdanpanah Y, Klein O, Gambiez L, Baron P, Desreumaux P, Marquis P, Cortot A, Quandalle P, Colombel JF. Impact of surgery on quality of life in Crohn’s disease. Am J Gastroenterol 1997;92:1897–1900
Thaler K, Dinnewitzer A, Oberwalder M, Weiss EG, Nogueras JJ, Wexner SD. Assessment of long-term quality of life after laparoscopic and open surgery for Crohn’s disease. Colorectal Dis 2005;7:375–381
Gardiner KR, Dasari BV. Operative management of small bowel Crohn’s disease. Surg Clin North Am 2007;87:587–610.
Jehle EC. Crohn disease—surgical standards. Swiss Surg 2003;9(3):157–166
Foster EN, Quiros JA, Prindiville TP. Long-term follow-up of the endoscopic treatment of strictures in pediatric and adult patients with inflammatory bowel disease. J Clin Gastroenterol 2008;42:880–885
Despott EJ, Gupta A, Burling D, Tripoli E, Konieczko K, Hart A, Fraser C. Effective dilation of small-bowel strictures by double-balloon enteroscopy in patients with symptomatic Crohn’s disease. Gastrointest Endosc 2009;70:1030–1036
Hashemi M, Novell JR, Lewis AA. Side-to-side stapled anastomosis may delay recurrence in Crohn’s disease. Dis Colon Rectum 1998;41:1293–1296
Yamamoto T. Factors affecting recurrence after surgery for Crohn’s disease. World J Gastroenterol 2005;11:3971–3979
Malireddy K, Larson DW, Sandborn WJ, Loftus EV, Faubion WA, Pardi DS, Qin R, Gullerud RE, Cima RR, Wolff B, Dozois EJ. Recurrence and impact of postoperative prophylaxis in laparoscopically treated primary ileocolic Crohn disease. Arch Surg 2010;145:42–47
Renna S, Orlando A, Orlando R, Cottone M Problems related to postoperative clinical relapse and endoscopic recurrence in Crohn’s disease. Recenti Prog Med 2009;100:469–478
Ferrante M, D’Haens G, Rutgeerts P, Vermeire S, Van Assche G Optimizing biologic therapies for inflammatory bowel disease (ulcerative colitis and Crohn’s disease). Curr Gastroenterol Rep 2009; 11: 504–508
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Skandalos, I., Angelopoulos, A., Margioulas, A. et al. Management of Crohn’s disease found during laparotomy for acute appendicitis. Hellenic J Surg 82, 391–396 (2010). https://doi.org/10.1007/s13126-010-0061-3
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13126-010-0061-3