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Indian Journal of Gastroenterology

, Volume 37, Issue 3, pp 276–277 | Cite as

Vitamin D levels in ulcerative colitis at first diagnosis: Does it “bell the cat”?

  • Mayank JainEmail author
  • Jayanthi Venkataraman
Letter
  • 95 Downloads

Sir,

Higher vitamin D levels in inflammatory bowel disease (IBD) are shown to be associated with improved quality of life [1], reduced rates of Clostridium difficile infection [2], reduced surgical rates [3], and lowered risk of cancers including colorectal cancer [4]. However, the presence and impact of vitamin D deficiency in treatment-naïve ulcerative colitis (UC) patients remain unexplored. Thus, the present case-control study was undertaken to compare the blood levels of vitamin D in patients with UC at the time of the first diagnosis and those in age- and sex-matched healthy controls.

This prospective study was done at two centers: Choithram Hospital and Research Centre, Indore (MJ) and Gleneagles Global Health City, Chennai (MJ, VJ) between 2012 and 2016. We included 30 treatment-naïve patients with UC with a confirmed diagnosis at registration. The diagnosis was based on clinical, endoscopic, and histopathological confirmation; we compared their data with 60 age- and...

References

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    Ananthakrishnan AN, Cagan A, Gainer VS, et al. Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Aliment Pharmacol Ther. 2014;39:1136–42.CrossRefPubMedPubMedCentralGoogle Scholar
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    Ananthakrishnan AN, Cheng SC, Cai T, et al. Association between reduced plasma 25-hydroxy vitamin D and increased risk of cancer in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014;12:821–7.CrossRefPubMedGoogle Scholar
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Copyright information

© Indian Society of Gastroenterology 2018

Authors and Affiliations

  1. 1.Department of GastroenterologyGleneagles Global Health CityChennaiIndia

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