Study of Distracted Bone in Maxilla: A Comparative Analysis
- 119 Downloads
Anterior maxillary distraction is one of the accepted modalities to treat hypoplastic maxilla. The study was undertaken to assess the maturation of the bone formed, which is measured by analyzing the amount of mineralization of the bone.
Materials and Methods
For the study 29 patients were chosen, who were divided into three groups. First group consist of patients who had undergone distraction osteogenesis. Second group has cleft patients and third group is the control group. A bone biopsy using trephine drill is obtained from the subjects. This sample is subjected to Fourier transform infrared spectroscopy (FTIR).
From the results a mineral to matrix ratio is obtained which is then compared between the three groups. There is a statistically significant difference between the mineralization of the three groups. The distracted bone shows the lowest mineralization while mineralization of the cleft bone is also less than the normal bone.
The study conclusively establishes that the distracted bone is not as mineralized as the normal bone. Although functionally the distracted bone is as good as the native bone and grafted bone as proved by the success rate of the implants placed. The study also highlights the use of FTIR for assessing the bone quality.
KeywordsDistraction osteogenesis Anterior maxillary distraction Bone quality FTIR
The authors would like to acknowledge the assistance of Mr.Ganesh, University Science Instrumentation Centre, Mangalore University for the FTIR analysis. This is a self-funded study done in the Yenepoya University, Mangalore, Karnataka, India. There are no conflicts of interest reported. Institutional ethical committee approval has been obtained for the study numbered YUEC 49/14/2/2014. Written patient consents were taken for publishing clinical photographs. All the authors have viewed the manuscript and agreed for submission.
- 1.Ilizarov GA (1989) The tension-stress effect on the genesis and growth of tissues. Part I. The influence of stability of fixation and soft-tissue preservation. Clin Orthop Relat Res 238:249–281Google Scholar
- 8.Karaharju EO, Aalto K, Kahri A et al (1993) Distraction bone healing. Clin Orthop 297:38Google Scholar
- 10.Figueiredo MM, Gamelas JAF, Martins AG (2012) Characterization of bone and bone-based graft materials using FTIR spectroscopy, infrared spectroscopy—Life and biomedical sciences, Prof. Theophanides Theophile (ed), ISBN: 978-953-51-0538-1Google Scholar
- 12.Delloye C, Delefortrie G, Coutelier L, Vincent A (1990) Bone regenerate formation in cortical bone during distraction lengthening: an experimental study. Clin Orthop Relat Res 250:34–42Google Scholar
- 18.Polley JW, Figueroa AA (2001) Distraction Osteogenesis for treatment of severe cleft maxillary deficiency with the RED technique. In: Cherkashin AM (ed) Craniofacial distraction osteogenesis. Mosby, St Louis, pp 485–493Google Scholar
- 29.Nyquist RA, Putzig CL, Leugers MA (1997) The handbook of infrared and raman spectra of inorganic compounds and organic salts, vol 1 and 4. Academic Press, San DiegoGoogle Scholar
- 31.Boskey A (2011) Using bone quality to assess fracture risk. Am Assoc Orthop Surg Now 5(9)Google Scholar
- 36.Álvarez-lloret P, Rodríguez-navarro AB, Romanek CS, Gaines KF, Congdon YJ (2006) Quantitative analysis of bone mineral using ftir XXVI REUNi ÓN (SEM)/XX REUNiÓN (SEA) – 2006Google Scholar