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Comparison of Extended Nasolabial Flap Versus Buccal Fat Pad Graft in the Surgical Management of Oral Submucous Fibrosis: A Prospective Pilot Study

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Abstract

Aim

To evaluate the application of extended nasolabial flap versus buccal fat pad graft in the surgical management of oral submucous fibrosis.

Settings and Design

This prospective study was carried out in the Department of Oral and Maxillofacial Surgery, Tamil Nadu Government Dental College and Hospital, Chennai.

Material and Methods

A total of 8 patients (6 men and 2 women) with age range from 21 to 65 years were selected for study. These 8 patients were randomly divided into two groups of four namely group 1 and group 2. In group 1 patients, reconstruction was planned with extended nasolabial flaps and in group 2 patients, reconstruction was planned with buccal fat pad graft respectively.

Statistical Analysis Used

Paired t test, Independent sample t test, ANOVA test.

Results

The mean preoperative mouth opening in group 1 was 8.5 mm and in group 2 was 11.75 mm. The mean increase in group 1 after one year of postoperative period was 21.50 mm and in group 2 was 24.75 mm.

Conclusions

In the present study, buccal fat pad graft proved to give better results as the interposition material as it has good patient acceptance, rapid epithelization, minimal donor site morbidity and minimal intra and postoperative complications.

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References

  1. Kaviraj BK (1911) An english translation of the Susruta Samhita Vol. II Nidhana-sthana to Kalp-sthana. 111–112 [Chapter 16]

  2. Schwartz J (1952). Atrophia idiopathica mucosa oris. In: Presented at the 11th International Dental Congress, London

  3. Joshi SG (1953) Submucous fibrosis of the palate and pillars. Indian J Otolaryngol 4:1–4

    Google Scholar 

  4. Gupta D, Sharma SC (1988) Oral submucous fibrosis—a newtreatment regimen. J Oral Maxillofac Surg 46:830–833

    Article  CAS  PubMed  Google Scholar 

  5. Pindborg JJ, Murti PR, Bhonsle RB, Gupta PC, Daftary DK, Mehta FS (1984) Oral submucous fibrosis as a precancerous condition. Scand J Dent Res 92:224–229

    CAS  PubMed  Google Scholar 

  6. Pillai R, Balaram P, Reddiar KS (1992) Pathogenesis of oral submucous fibrosis. Cancer 69:2011

    Article  CAS  PubMed  Google Scholar 

  7. Paymaster JC (1956) Cancer of the buccal mucosa: clinical study of 650 cases in Indian patients. Cancer 9:431–435

    Article  CAS  PubMed  Google Scholar 

  8. Murti PR, Bhonsale RB, Pindborg JJ, Daftary DK, Gupta PC, Mehta FS (1985) Malignant transformation rate in oral submucous fibrosis over a 17 year period. Commun Dent Oral Epidemiol 13:340–341

    Article  CAS  Google Scholar 

  9. Cox SC, Walker DM (1996) Oral submucous fibrosis: a review. Aust Dent J 41:294

    Article  CAS  PubMed  Google Scholar 

  10. Tang JG, Jian XF, Gao ML, Ling TY, Zhang KH (1997) Epidemiological survey of oral submucous fibrosis in Xiangtan City, Hunan Province, China. Commun Dent Oral Epidemiol 25:177

    Article  CAS  Google Scholar 

  11. Yen DJC (1982) Surgical treatment of submucous fibrosis. Oral Surgery Oral Med Oral Pathol 54(3):269–272

    Article  CAS  Google Scholar 

  12. Khanna JN, Andrade NN (1995) Oral submucous fibrosis: a new concept in surgical management—report of 100 cases. Int J Oral Maxillofac Surg 24:433–439

    Article  CAS  PubMed  Google Scholar 

  13. Jiang X, Hu J (2009) Drug treatment of oral submucous fibrosis: a review of the literature. J Oral Maxillofac Surg 67:1510–1515

    Article  PubMed  Google Scholar 

  14. Mokal NJ, Raje RS, Ranade SV et al (2005) Release of oral submucous fibrosis and reconstruction using superficial temporal fascia flap and split skin graft—a new technique. Br J Plast Reconstr Surg 58:1055

    Article  CAS  Google Scholar 

  15. Wei FC, Chang YM, Kildal M, Tsang WS, Chen HC (2001) Bilateral small radial forearm flaps for the reconstruction of buccal mucosa after surgical release of submucosal fibrosis: a new reliable approach. Plast Reconstr Surg 107:1679–1683

    Article  CAS  PubMed  Google Scholar 

  16. Lee JT, Cheng LF, Chen PR, Wang CH, Hsu H, Chien SH et al (2007) Bipaddled radial forearm flap for the reconstruction of bilateral buccal defects in oral submucous fibrosis. Int J Oral Maxillofac Surg 36:615–619

    Article  PubMed  Google Scholar 

  17. Tsao CK, Wei FC, Chang YM et al (2010) Reconstruction of the buccal mucosa following release for submucous fibrosis using two radial forearm flaps from a single donor site. J Plast Reconstr Aesthet Surg 63:1117

    Article  PubMed  Google Scholar 

  18. Huang JJ, Wallace C, Lin JY et al (2010) Two small flaps from one anterolateral thigh donor site for bilateral buccal mucosa reconstruction after release of submucous fibrosis and/or contracture. J Plast Reconstr Aesthet Surg 63:440

    Article  PubMed  Google Scholar 

  19. Ko EC, Shen YH, Yang CF, Huang IY, Shieh TY, Chen CM (2009) Artificial dermis as the substitute for split-thickness skin graft in the treatment of oral submucous fibrosis. J Craniofac Surg 20:443–445

    Article  PubMed  Google Scholar 

  20. Yeh CJ (1996) Application of the buccal fat pad to the surgical treatment of oral submucous fibrosis. Int J Oral Maxillofac Surg 25:130–133

    Article  CAS  PubMed  Google Scholar 

  21. Borle RM, Nimonkar PV, Rajan R (2009) Extended nasolabial flaps in the management of oral submucous fibrosis. Br J Oral Maxillofac Surg 47:382

    Article  CAS  PubMed  Google Scholar 

  22. Chang YM, Tsai CY, Kildal M, Wei FC (2004) Importance of coronoidotomy and masticatory muscle myotomy in surgical release of trismus caused by submucous fibrosis. Plast Reconstr Surg 113:1949–1954

    Article  PubMed  Google Scholar 

  23. Canniff JP, Harvey W, Harris M (1986) Oral submucous fibrosis- its pathogenesis and management. Br Dent J 160:429–433

    Article  CAS  PubMed  Google Scholar 

  24. Gupta DS, Dolas R, Iqbal A (1992) “Treatment modalities in submucous fibrosis- How they stand today?” Study of 600 cases. Indian J Oral Maxillofac Surg 7(43):1

    Google Scholar 

  25. Bhonsle RB, Murthi PR, Gupta PC, Mehta FS (1976) Reverse dhumti smoking in Goa—an epidemiological study of 5449 villages for oral precancerous lesions. Indian J Cancer 13:301–305

    CAS  PubMed  Google Scholar 

  26. Aziz SR (2008) Oral submucous fibrosis: case report and review of diagnosis and treatment. J Oral Maxillofac Surg 66:2386–2389

    Article  PubMed  Google Scholar 

  27. Mehrotra D, Pradhan R, Gupta S (2009) Retrospective comparison of surgical treatment modalities in 100 patients with oral submucous fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:e1

    Article  PubMed  Google Scholar 

  28. Gupta S, Reddy MVR, Harinath BC (2004) Role of oxidative stress and antioxidants in aetiopathogenesis and management of oral submucous fibrosis. Indian J Clin Biochem 19:138

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  29. Kumar A, Sharma SC, Sharma P et al (1991) Beneficial effect of oral zinc in the treatment of oral submucous fibrosis. Indian J Pharmacol 23:236

    Google Scholar 

  30. Morawetz G, Katsikeris N, Weinberg S, Listrom R (1987) Oral submucous fibrosis. J Oral Maxillofac Surg 16:609–614

    Article  CAS  Google Scholar 

  31. Haque MF, Meghji S, Nazir R et al (2001) Interferon gamma may reverse oral submucous fibrosis. J Oral Pathol Med 30:12

    Article  CAS  PubMed  Google Scholar 

  32. Lin HJ, Lin JC (2007) Treatment of oral submucous fibrosis by collagenase: effects on oral opening and eating function. Oral Dis 13:407

    Article  PubMed  Google Scholar 

  33. Sharma JK, Gupta AK, Mukhija RD et al (1987) Clinical experience with the use of peripheral vasodilator in oral disorders. Int J Oral Maxillofac Surg 16:695

    Article  CAS  PubMed  Google Scholar 

  34. Borle RM, Borle SR (1991) Management of oral submucous fibrosis: a conservative approach. J Oral Maxillofac Surg 49:788–791

    Article  CAS  PubMed  Google Scholar 

  35. Kothari MC, Hallur N, Sikkerimath B, Gudi S, Kothari CR (2012) Coronoidectomy, masticatory myotomy and buccal fat pad graft in management of advanced oral submucous fibrosis. Int J Oral Maxillofac Surg 41:1416–1421

    Article  CAS  PubMed  Google Scholar 

  36. Lai DR (1995) Clinical evaluation of different treatment methods for oral submucous fibrosis. A 10 –year experience with 150 cases. J Oral Pathol Med 24:402–406

    Article  CAS  PubMed  Google Scholar 

  37. Khanna JN (1995) Oral submucous fibrosis: a new concept in surgical management: report of 100 cases. IJOMS 24:433–439

    CAS  Google Scholar 

  38. Hosaka Y, Tsukagoshi T, Sasaki E, Yokoyama S (1999) The use of otherwise redundant skin to provide nasal lining in the reconstruction of full—thickness alar defects by nasolabial flap repair. Br J Plast Surg 52:29–32

    Article  CAS  PubMed  Google Scholar 

  39. Gewirtz HS, Eilber FR, Zream HA (1978) Use of nasolabial flap for reconstruction of the floor of the mouth. Am J Surg 136:508–511

    Article  CAS  PubMed  Google Scholar 

  40. Morgan RF, Chambers RG, Jaques DA, Hoopes JE (1981) Nasolabial flap in intraoral reconstruction—review of 55 cases. Am J Surg 142:448–450

    Article  CAS  PubMed  Google Scholar 

  41. Kavarana NM, Bhathena HM (1987) Surgery for severe trismus in submucous fibrosis. Br J Plast Surg 40:407–409

    Article  CAS  PubMed  Google Scholar 

  42. Rapidis Alexander D (2000) The use of the Buccal fat pad for Reconstruction of oral defects: review of literature and report of 15 cases. J Oral Maxillofac 58:158–163

    Article  CAS  Google Scholar 

  43. Martin Granizo R (1997) Use of buccal fat pad to repair intraoral defects: review of 30 cases. Brt J of Maxillofac Surg 35:81–84

    Article  CAS  Google Scholar 

  44. Alkan A (2003) The reconstruction of oral defects with Buccal Fat Pad. Swiss Med Wkly 133:465–470

    PubMed  Google Scholar 

  45. Tideman H, Bosanquet A, Scott J (1986) Use of the buccal fat pad as a pedicled graft. J Oral Maxillofac Surg 44:435

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Sandeep B. Patil.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Patil, S.B., Durairaj, D., Suresh Kumar, G. et al. Comparison of Extended Nasolabial Flap Versus Buccal Fat Pad Graft in the Surgical Management of Oral Submucous Fibrosis: A Prospective Pilot Study. J. Maxillofac. Oral Surg. 16, 312–321 (2017). https://doi.org/10.1007/s12663-016-0975-6

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