Skip to main content
Log in

Treatment of Sarcoptic mange infestation in rabbits with long acting injectable ivermectin

  • Short Communication
  • Published:
Journal of Parasitic Diseases Aims and scope Submit manuscript

Abstract

Sarcoptic mange infestation is one of the major constrains in commercial rabbit rearing due to their ability to produce negative impact on the growth rates and feed conversion efficiency. Ten adult rabbits presented with the history of anorexia, pruritis and crusty lesion in ear, face and legs were selected for the study. Skin scraping examination revealed presence of Sarcoptes scabiei. The subcutaneous administration of single dose long acting injectable Ivermectin (3.15% w/v) formulation at a dose rate of 700 mcg/kg body weight was found to be safe, effective and less time consuming for the management of Sarcoptic mange in naturally infested rabbits. The skin scrapings collected from all the rabbits under study on days 14 and 28 were negative on both instances indicating rapid elimination of S. scabiei with a single dose of long acting ivermectin. No relapse of infestation was observed in any of the rabbits under treatment during the 6 month observation period following the treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  • Alvinerie M, Sutra JF, Galtier P (1993) Ivermectin in goat plasma and milk after subcutaneous injection. Vet Res 24(5):417–421

    PubMed  CAS  Google Scholar 

  • Alvinerie M, Escudero E, Sutra JF, Eeckhoutte C, Galtier P (1998) The pharmacokinetics of moxidectin after oral and subcutaneous administration to sheep. Vet Res 29(2):113–118

    PubMed  CAS  Google Scholar 

  • Arends JJ, Skogerboe TL, Ritzhaupt LK (1999) Persistent efficacy of doramectin and ivermectin against experimental infestations of Sarcoptes scabiei var. suis in swine. Vet Parasitol 82(1):71–79

    Article  CAS  Google Scholar 

  • Bhardwaj RK, Ahmad Mir I, Ahmad O, Kumar A, Wahid A, Bhardwaj D (2012) An outbreak of mange in rabbits. Indian Vet J 89(12):78

    Google Scholar 

  • Darzi MM, Mir MS, Shahardar RA, Pandit BA (2007) Clinico-pathological, histochemical and therapeutic studies on concurrent sarcoptic and notoedric acariosis in rabbits (Oryctolagus cuniculus). Veterinarski arhiv 77(2):167–175

    Google Scholar 

  • Davies PR, Moore MJ, Pointon AM (1991) Seasonality of sarcoptic mange in pigs in South Australia. Aust Vet J 68(12):390–392

    Article  CAS  Google Scholar 

  • Gokbulut C, Biligili A, Kart A, Turgut C (2010) Plasma dispositions of ivermectin, doramectin and moxidectin following subcutaneous administration in rabbits. Lab Anim 44(2):138–142

    Article  CAS  Google Scholar 

  • Kachhawa JP, Kachhawaha S, Srivastava M, Chahar A, Singh NK (2013) Therapeutic management of scabies in rabbits. Intas Polivet 14(2):306–309

    Google Scholar 

  • Kumar A, Kumar R, Archana, Kumari N (2018a) A successful treatment report on rabbits infected with sarcoptic mange. Pharma Innov J 7(2):1–3

    Google Scholar 

  • Kumar M, Nath A, Debbarma S, Bhattacharjee S, Monsang S, Bijwal D, Raghavan S (2018b) Comparative curative efficacy of ivermectin and ivermectin with vitamin supplementation treatment against naturally infested Sarcoptes scabiei Mite in rabbits: a retrospective study. Int J Livest Res 8(12):82–86

    Google Scholar 

  • Lifschitz A, Virkel G, Ballent M, Sallovitz J, Imperiale F, Pis A, Lanusse C (2007) Ivermectin (3.15%) long-acting formulations in cattle: absorption pattern and pharmacokinetic considerations. Vet Parasitol 147(3–4):303–310

    Article  CAS  Google Scholar 

  • McCarthy JS, Kemp DJ, Walton SF, Currie BJ (2004) Scabies: more than just an irritation. Postgrad Med J 80(945):382–387

    Article  CAS  Google Scholar 

  • Nazir T, Katoch R, Yadav A, Godara R (2016) Comparative efficacy of pour-on eprinomectin and ivermectin against Sarcoptes scabiei in buffaloes. J Parasit Dis 40(2):359–361

    Article  CAS  Google Scholar 

  • Omshi FSH, Abbasalipourkabir R, Abbasalipourkabir M, Nabyan S, Bashiri A, Ghafourikhosroshahi A (2018) Effect of vitamin A and vitamin C on attenuation of ivermectin-induced toxicity in male Wistar rats. Environ Sci Pollut Res 25(29):29408–29417

    Article  CAS  Google Scholar 

  • Panigrahi PN, Mohanty BN, Gupta AR, Patra RC, Dey S (2016) Concurrent infestation of Notoedres, Sarcoptic and Psoroptic acariosis in rabbit and its management. J Parasit Dis 40(3):1091–1093

    Article  CAS  Google Scholar 

  • Prakash MA, Soundararajan C, Nagarajan K, Gnanaraj PT, Saravanakumar VR (2017) Sarcoptic mange infestation in rabbits in an organized farm at Tamil Nadu. J Parasit Dis 41(2):429–432

    Article  Google Scholar 

  • Reddy CBK, Kumari KN, Sundar NS, Kumar NV (2016) Otitis externa associated with scabies and its zoonotic importance. Int J Sci Environ Technol 5(6):4370–4374

    Google Scholar 

  • Scott DW, Miller WH, Griffin GE (2001) Dermatosis of pet rodents, rabbits and ferrets. Muller and kirks small animal dermatology. W.B. Saunders, Philadelphia, pp 1448–1449

  • Singh B, Gupta D, Tiwari A, Shukla PC (2017) Therapeutic management of sarcoptic mange in rabbit: a case report. Glob J Bio-Sci Biotechnol 6(2):398–399

    Google Scholar 

  • Soulsby EJL (1982) Helminths, arthropods and protozoa of domesticated animals, 7th edn. Bailliere Tindall, London

    Google Scholar 

  • Voyvoda H, Ulutas B, Eren H, Karagenc T, Bayramli G (2005) Use of doramectin for treatment of sarcoptic mange in five Angora rabbits. Vet Dermatol 16(4):285–288

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

KS: Conceived and designed the analysis, collected the data, performed the analysis, and written the manuscript. SA: Collected the data, performed the analysis. SAS: Conceived and designed the analysis, collected the data. SP: Conceived and designed the analysis.

Corresponding author

Correspondence to Khan Sharun.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

The study was conducted in clinical cases of Sarcoptes scabiei infestation in rabbits presented to Veterinary Polyclinic, Mannarkkad, Palakkad and does not require any permission from animal ethics committee. All protocols followed were as per the guidelines from the standard textbooks in Veterinary Medicine and were ethical.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sharun, K., Anjana, S., Sidhique, S.A. et al. Treatment of Sarcoptic mange infestation in rabbits with long acting injectable ivermectin. J Parasit Dis 43, 733–736 (2019). https://doi.org/10.1007/s12639-019-01137-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12639-019-01137-z

Keywords

Navigation