Impact of ENIGMA trials on nitrous oxide: a survey of Canadian anesthesiologists and residents

Correspondence
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Notes

Conflict of interest

None declared.

Editorial responsibility

This submission was handled by Dr. Gregory L. Bryson, Deputy Editor-in-Chief, Canadian Journal of Anesthesia.

Funding

None

Supplementary material

12630_2018_1060_MOESM1_ESM.pdf (45 kb)
Supplementary material 1 (PDF 44 kb)

References

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    Myles PS, Leslie K, Chan MT, et al. Avoidance of nitrous oxide for patients undergoing major surgery: a randomized controlled trial. Anesthesiology 2007; 107: 221-31.CrossRefPubMedGoogle Scholar
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    Myles PS, Leslie K, Chan MT, et al. The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial. Lancet 2014; 384: 1446-54.CrossRefPubMedGoogle Scholar
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    Myles PS, Chan MT, Kasza J, et al. Severe nausea and vomiting in the evaluation of nitrous oxide in the gas mixture for anesthesia II trial. Anesthesiology 2016; 124: 1032-40.CrossRefPubMedGoogle Scholar
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    Sulbaek Andersen MP, Nielsen OJ, Wallington TJ, Karpichev B, Sander SP. Assessing the impact on global climate from general anesthetic gases. Anesth Analg 2012; 114: 1081-5.CrossRefPubMedGoogle Scholar

Copyright information

© Canadian Anesthesiologists' Society 2018

Authors and Affiliations

  1. 1.Department of AnesthesiaMcMaster UniversityHamiltonCanada

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