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Les cas d’atrophie multisystématisée existent-ils dans la population âgée et sont-ils plus fréquemment associés à des troubles cognitifs ?

Does multisystem atrophy exist in the elderly and is it likely associated with a cognitive impairment?

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Les cahiers de l'année gérontologique

Résumé

Reconnaître l’atrophie multisystématisée (AMS), une affection neurodégénérative rare associant dysautonomie, syndrome parkinsonien, pyramidal et cérébelleux, est difficile chez le sujet âgé. Mais si poser le diagnostic d’AMS chez un patient de moins de 60 ans est important en termes de pronostic, tel est moins le cas chez le sujet âgé. Chez ce dernier, c’est en effet le plus souvent la résultante globale des divers dysfonctionnements neurologiques quelle qu’en soit l’origine qui fera le pronostic plus que la nature des processus lésionnels en cause.

Abstract

To identify a multisystem atrophy (MSA), a rare neurodegenerative disease combining autonomic dysfunction, parkinsonism, pyramidal symptoms and cerebellar ataxia, is difficult in the elderly. Whereas diagnosing MSA is useful in term of prognosis in a patient younger than 60, it is not the case in aged persons. In this population, the prognosis is often more linked to the overall result of the different nervous system dysfunction whatever the mechanisms than the direct cause of the lesions.

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Authors and Affiliations

  1. CIC0004 et Clinique neurologique, CHU Nantes, F-44093, Nantes, France

    P. Damier

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  1. P. Damier
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Correspondence to P. Damier.

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Damier, P. Les cas d’atrophie multisystématisée existent-ils dans la population âgée et sont-ils plus fréquemment associés à des troubles cognitifs ?. cah. année gerontol. 4, 63–67 (2012). https://doi.org/10.1007/s12612-012-0263-4

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  • DOI: https://doi.org/10.1007/s12612-012-0263-4

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