Peak Expiratory Flow as an Index of Frailty Syndrome in Older Adults: A Cross-Sectional Study

Abstract

Objectives

to compare the obtained and predicted peak expiratory flow (PEF) values between frail, pre-frail, and non-frail older adults; verify the association between PEF and FS; and establish cut-off points for PEF as determinants of frailty syndrome (FS).

Design

Cross-sectional study.

Location

Macapa, Amapa, Brazil.

Participants

Community-based study community-dwelling older people.

Methods

PEF was evaluated using a peak-flow meter and FS was evaluated using Fried’s frailty phenotype. The statistical analyses performed included a multinomial logistic regression model and Receiver Operating Characteristic (ROC) curves to establish cut-off points for discriminating FS.

Results

409 older adults with a mean age of 70.09±7.22 years were evaluated; of these, 58.7% were pre-frail, and 12.7% were frail. PEF was lower in frail than in pre-frail participants, and lower in pre-frail than in non-frail. Frail and pre-frail older adults obtained lower PEF values than predicted. PEF (% Predicted) was inversely associated with frailty and pre-frailty even after adjustment. Cut-off points were established to discriminate the presence of frailty in older men (PEF≤350L/min; AUC=0.669; sensitivity=76.92%; specificity=52%) and women (PEF≤220L/min; AUC=0.597; sensitivity=71.79%; specificity=46.98%).

Conclusions

Frail and pre-frail older adults presented significantly lower PEF than non-frail participants, and these values were lower than predicted. PEF was inversely associated with frailty and pre-frailty. PEF cut-off points can be used as a complementary method to indicate frailty in community-dwelling older adults.

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Funding

This research was financed by the Foundation for Research Support of the State of Amapa (FAPEAP, Concession no 250.203.029/2016).

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Corresponding author

Correspondence to Maycon Sousa Pegorari.

Additional information

Ethicals declaration

This study received approval from the Research Ethics Committee of the Federal University of Amapa, number 1.738.671.

Conflict of interest disclosure

There was no conflict of interest.

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Magave, J.A., Bezerra, S.J.S., Matos, A.P. et al. Peak Expiratory Flow as an Index of Frailty Syndrome in Older Adults: A Cross-Sectional Study. J Nutr Health Aging (2020). https://doi.org/10.1007/s12603-020-1423-3

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Key words

  • Aging
  • frail elderly
  • respiratory function tests
  • peak expiratory flow rate
  • respiratory muscles