Underweight in Men had a Closer Relationship with Falls than Women in Centenarians

Abstract

The aim of the study was to assess the relationship between underweight and falls. It was a cross-sectional study in community-based participants from China Hainan Centenarian Cohort Study (CHCCS). A total of 942 centenarians (mean ages were 102.4 years in men and 102.9 years in women, 21.8% were semi-supercentenarians, and 3.2% were supercentenarians) were enrolled from July 2014 to December 2016. Height and weight were measured according to the standard protocol. Participants were interviewed face to face to self-report falls for recent 3 months. The risks of future falls were evaluated by Morse Fall Scale (MFS). The mean body mass index (BMI) was 19.04±2.79 kg/m2 in men and 18.07±3.27 kg/m2 in women. The 3-month incidences of once fall were 10.3% in men and 13.4% in women, recurrent falls were 15.4% in men and 13.4% in women, future high risks of falls were 36.6% in men and 44.3% in women. There were underweight by gender interactions on at least one fall (OR=1.39, 95% CI=1.04–1.86, P=0.026) and future high fall risk (OR=1.39, 95% CI=1.07–1.80, P=0.014). Men with underweight had higher ratios of at least one fall (OR=4.12, 95% CI=1.59–10.70, P=0.004), recurrent falls (OR=6.71, 95% CI=1.69–26.63, P=0.007) and high risk of future falls (OR=2.44, 95% CI=1.27–4.70, P=0.007), while women with underweight was only associated with high risk of future falls (OR=1.37, 95% CI=1.01–1.85, P=0.043). Compared with normal weight and overweight, underweight in men had a higher MFS Score (increased by average 7.6 points, P=0.010), yet this trend was not observed in women counterparts. Underweight was associated with incidences of 3-month and future high fall risk in centenarians, which was more pronounced in men. Underweight could be a marker in identifying potential falls in long-lived people, especially men, who need further measures to gaining weight to normal and preventing falling.

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Acknowledgement

Author Contributions: ZYJ, YY, FSH, ZQ, NCX, LFX, ZF and ZYL: contributed to the design of the study, data collection process, statistical analysis and drafted the manuscript. All authors read and approved the final manuscript.

Funding

Funding disclosure: This work was supported by grants from National Key R&D Program of China (2018YFC2000400), National Natural Science Foundation of China (81903392, 819003S7, 81941021), National S&T Resource Sharing service platform Project of China (YCZYPT[2018]07), General Hospital of PLA Medical Big Data R&D Project (MBD2018030), China Postdoctoral Science Foundation funded project (2019M6S03S9).

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Correspondence to Ya-Li Zhao or Yao Yao.

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Conflict of Interest: The authors declare that they have no competing interests.

Ethical standards: The study was approved by Ethics Committee of Hainan Hospital of Chinese PLA General Hospital (No. 301hn11201601).

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Zhang, Y., Fu, S., Zhu, Q. et al. Underweight in Men had a Closer Relationship with Falls than Women in Centenarians. J Nutr Health Aging (2020). https://doi.org/10.1007/s12603-020-1411-7

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Key words

  • Underweight
  • falls
  • gender difference
  • centenarians