The Journal of Physiological Sciences

, Volume 68, Issue 3, pp 281–291 | Cite as

Does patchouli oil change blood platelet monoamine oxidase-A activity of adult mammals?

  • Md. Fazlul Karim
  • Soumyabrata Banerjee
  • Mrinal K. Poddar
Original Paper

Abstract

Patchouli oil, an essential aroma oil extracted from patchouli leaf during short-term exposure with five and ten drops either inhibited (at 1 or 2 h) or stimulated (at 4 h) the platelet MAO-A activity depending on the dosages of the aroma oil mainly due to inhibition or stimulation of its K m. The long-term 15 consecutive days exposure (with two or five drops) of patchouli oil, on the other hand, maximally stimulated the platelet MAO-A activity with five drops patchouli oil for 1 h exposure, but further continuation of its exposure with same doses (two or five drops) for 30 consecutive days significantly stimulated (with two drops) and inhibited (with five drops) the platelet MAO-A activity due to stimulation and inhibition respectively of its corresponding both K m and V max. These results thus suggest that this aroma oil exposure may modulate the blood platelet serotonergic regulation depending on the dose, duration, and conditions of exposure.

Keywords

Blood platelet Monoamine oxidase-A Patchouli oil 

Notes

Acknowledgments

The authors are thankful to Prof. S. Sengupta, Department of Statistics, University of Calcutta for his kind help in statistical analysis of the data. We are also thankful to the University of Calcutta, Kolkata, India, the Indian Council of Medical Research, New Delhi, India, University Grants Commission, New Delhi, India for their financial help.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

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Copyright information

© The Physiological Society of Japan and Springer Japan 2017

Authors and Affiliations

  • Md. Fazlul Karim
    • 1
  • Soumyabrata Banerjee
    • 1
  • Mrinal K. Poddar
    • 1
  1. 1.Department of BiochemistryUniversity of CalcuttaKolkataIndia

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