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Bijblijven

, Volume 33, Issue 1, pp 16–25 | Cite as

Maternale kinkhoestvaccinatie

  • Laura Antonise-Kamp
  • Birthe Lehmann
  • Nicoline van der Maas
Article

Samenvatting

Pasgeborenen en jonge, nog niet of onvoldoende gevaccineerde zuigelingen vormen de belangrijkste risicogroep voor het krijgen van een ernstige kinkhoestinfectie. Vaccineren van zwangere vrouwen is een effectieve manier om deze groep te beschermen tegen kinkhoest. Zwangere vrouwen maken beschermende antistoffen aan die zij via de placenta aan hun kind doorgeven. Op deze manier zijn zuigelingen de eerste levensmaanden beschermd tegen (een ernstig verloop van) kinkhoest.

Eind 2015 heeft de Gezondheidsraad het advies uitgebracht om kinkhoestvaccinatie tijdens de zwangerschap aan te bieden via een nationaal programma. De minister van Volksgezondheid, Welzijn en Sport (VWS) is voornemens dit advies over te nemen, mits het uitvoerbaar en betaalbaar blijkt te zijn. Zij zal hierover binnenkort een definitief besluit nemen.

Literatuur

  1. 1.
    Greeff SC de, Melker HE de, Gageldonk PG van, Schellekens JF, Klis FR van der, Mollema L, et al. Seroprevalence of pertussis in The Netherlands: evidence for increased circulation of Bordetella pertussis. PLOS ONE. 2010;5(12):e14183.CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Gezondheidsraad. Vaccinatie tegen kinkhoest: doel en strategie. Den Haag: Gezondheidsraad; 2015.Google Scholar
  3. 3.
    Greeff SC de, Melker HE de, Westerhof A, Schellekens JF, Mooi FR, Boven M van. Estimation of household transmission rates of pertussis and the effect of cocooning vaccination strategies on infant pertussis. Epidemiology. 2012;23(6):852–60.CrossRefPubMedGoogle Scholar
  4. 4.
    Greeff SC de, Mooi FR, Westerhof A, Verbakel JM, Peeters MF, Heuvelman CJ, et al. Pertussis disease burden in the household: how to protect young infants. Clin Infect Dis. 2010;50(10):1339–45.CrossRefPubMedGoogle Scholar
  5. 5.
    Kohler PF, Farr RS. Elevation of cord over maternal IgG immunoglobulin: evidence for an active placental IgG transport. Nature. 1966;210(5040):1070–1.CrossRefPubMedGoogle Scholar
  6. 6.
    Malek A, Sager R, Kuhn P, Nicolaides KH, Schneider H. Evolution of maternofetal transport of immunoglobulins during human pregnancy. Am J Reprod Immunol. 1996;36(5):248–55.CrossRefPubMedGoogle Scholar
  7. 7.
    Halperin BA, Morris A, Mackinnon-Cameron D, Mutch J, Langley JM, McNeil SA, et al. Kinetics of the antibody response to tetanus-diphtheria-acellular pertussis vaccine in women of childbearing age and postpartum women. Clin Infect Dis. 2011;53(9):885–92.CrossRefPubMedGoogle Scholar
  8. 8.
    Eberhardt CS, Blanchard-Rohner G, Lemaitre B, Boukrid M, Combescure C, Othenin-Girard V, et al. Maternal immunization earlier in pregnancy maximizes antibody transfer and expected infant seropositivity against pertussis. Clin Infect Dis. 2016;62(7):829–36.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Maertens K, Cabore RN, Huygen K, Hens N, Van Damme P, Leuridan E. Pertussis vaccination during pregnancy in Belgium: results of a prospective controlled cohort study. Vaccine. 2016;34(1):142–50.CrossRefPubMedGoogle Scholar
  10. 10.
    Ladhani SN, Andrews NJ, Southern J, Jones CE, Amirthalingam G, Waight PA, et al. Antibody responses after primary immunization in infants born to women receiving a pertussis-containing vaccine during pregnancy: single arm observational study with a historical comparator. Clin Infect Dis. 2015;61(11):1637–44.CrossRefPubMedGoogle Scholar
  11. 11.
    Liese JG, Renner C, Stojanov S, Belohradsky BH, Munich Vaccine Study G. Clinical and epidemiological picture of B pertussis and B parapertussis infections after introduction of acellular pertussis vaccines. Arch Dis Child. 2003;88(8):684–7.CrossRefPubMedPubMedCentralGoogle Scholar
  12. 12.
    Wendelboe AM, Van Rie A, Salmaso S, Englund JA. Duration of immunity against pertussis after natural infection or vaccination. Pediatr Infect Dis J. 2005;24(5 Suppl):S58–S61.CrossRefPubMedGoogle Scholar
  13. 13.
    Zhang L, Prietsch SO, Axelsson I, Halperin SA. Acellular vaccines for preventing whooping cough in children. Cochrane Database Syst Rev. 2014;9:CD001478. doi: 10.1002/14651858.cd001478.pub6.Google Scholar
  14. 14.
    Amirthalingam G, Andrews N, Campbell H, Ribeiro S, Kara E, Donegan K, et al. Effectiveness of maternal pertussis vaccination in England: an observational study. Lancet. 2014;384(9953):1521–8.CrossRefPubMedGoogle Scholar
  15. 15.
    Dabrera G, Amirthalingam G, Andrews N, Campbell H, Ribeiro S, Kara E, et al. A case-control study to estimate the effectiveness of maternal pertussis vaccination in protecting newborn infants in England and Wales, 2012–2013. Clin Infect Dis. 2015;60(3):333–7.CrossRefPubMedGoogle Scholar
  16. 16.
    Maas N van der, Dijs-Elsinga J, Kemmeren J, Lier A van, Knol M, Melker H de. Safety of vaccination against influenza A (H1N1) during pregnancy in the Netherlands: results on pregnancy outcomes and infant’s health: cross-sectional linkage study. BJOG. 2016;123(5):709–17.CrossRefPubMedGoogle Scholar
  17. 17.
    Donegan K, King B, Bryan P. Safety of pertussis vaccination in pregnant women in UK: observational study. BMJ. 2014;349:g4219.CrossRefPubMedPubMedCentralGoogle Scholar
  18. 18.
    Kharbanda EO, Vazquez-Benitez G, Lipkind HS, Klein NP, Cheetham TC, Naleway A, et al. Evaluation of the association of maternal pertussis vaccination with obstetric events and birth outcomes. JAMA. 2014;312(18):1897–904.CrossRefPubMedGoogle Scholar
  19. 19.
    Vizzotti C, Neyro S, Katz N, Juarez MV, Carrega PME, Aquino A, et al. Maternal immunization in Argentina: a storyline from the prospective of a middle income country. Vaccine. 2015;33:6413. doi: 10.1016/j.vaccine.2015.07.109.CrossRefPubMedGoogle Scholar
  20. 20.
    Van der Maas NAT, Aerde K van, Bont LJ, Bekker MN, Rots N, Melker HE de. Infectiepreventie bij zuigelingen door maternale vaccinatie. Ned Tijdschr Geneeskd. 2016;160:D411.PubMedGoogle Scholar
  21. 21.
    Morgan JL, Baggari SR, McIntire DD, Sheffield JS. Pregnancy outcomes after antepartum tetanus, diphtheria, and acellular pertussis vaccination. Obstet Gynecol. 2015;125(6):1433–8.CrossRefPubMedGoogle Scholar

Copyright information

© Bohn Stafleu van Loghum 2016

Authors and Affiliations

  • Laura Antonise-Kamp
    • 1
  • Birthe Lehmann
    • 1
  • Nicoline van der Maas
    • 1
  1. 1.BilthovenNederland

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