Better Is the Evolution of Good: How IVUS and OCT Have Transformed PCI


Purpose of Review

We seek to provide a focused appraisal of the most recent outcomes data for intravascular ultrasound (IVUS) and optical coherence tomography (OCT).

Recent Findings

There are multiple randomized control trials and meta-analyses investigating the effects of these two intravascular imaging (IVI) modalities on clinical decision-making and long-term clinical outcomes in percutaneous coronary intervention (PCI). While the effects of IVUS have been studied for decades, OCT is a newer form of IVI with less experience and data on its use in clinical practice.


IVUS-guided PCI has beneficial effects on mortality, stent thrombosis, target lesion/target vessel revascularization, and major adverse cardiac events when compared to angiography alone. While less data exists for OCT-guided PCI, early studies suggest it is at least non-inferior to IVUS for many of the same outcomes. However, future investigations should focus on how clinical outcomes are changed by these two IVI modalities when compared head-to-head.

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American College of Cardiology Foundation


American Heart Association


Bare metal stent


Chronic total occlusion


Drug-eluting stent


Intravascular imaging


Intravascular ultrasound




Major adverse cardiac events


Myocardial infarction


Optical coherence tomography


Percutaneous coronary intervention


Randomized control trial


Society for Cardiovascular Angiography and Interventions


Stent thrombosis


ST-elevation myocardial infarction


Target lesion revascularization


Target vessel failure


Target vessel revascularization


Important reference


Very important reference


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. 1.

    Shapiro TA, Herrmann HC. Coronary angiography and interventional cardiology. Curr Opin Radiol. 1992;4(4):55–64.

    CAS  PubMed  Google Scholar 

  2. 2.

    Leape LL, Park RE, Bashore TM, Harrison JK, Davidson CJ, Brook RH. Effect of variability in the interpretation of coronary angiograms on the appropriateness of use of coronary revascularization procedures. Am Heart J. 2000;139(1 Pt 1):106–13.

    CAS  Article  PubMed  Google Scholar 

  3. 3.

    Girasis C, Onuma Y, Schuurbiers JC, Morel MA, van Es GA, van Geuns RJ, et al. Validity and variability in visual assessment of stenosis severity in phantom bifurcation lesions: a survey in experts during the fifth meeting of the European Bifurcation Club. Catheter Cardiovasc Interv. 2012;79(3):361–8.

    Article  PubMed  Google Scholar 

  4. 4.

    Parviz Y, Shlofmitz E, Fall KN, Konigstein M, Maehara A, Jeremias A, et al. Utility of intracoronary imaging in the cardiac catheterization laboratory: comprehensive evaluation with intravascular ultrasound and optical coherence tomography. Br Med Bull. 2018;125(1):79–90.

  5. 5.

    Mintz GS, Nissen SE, Anderson WD, Bailey SR, Erbel R, Fitzgerald PJ, et al. American College of Cardiology Clinical Expert Consensus Document on standards for acquisition, measurement and reporting of intravascular ultrasound studies (IVUS). A report of the American College of Cardiology Task Force on clinical expert consensus documents. J Am Coll Cardiol. 2001;37(5):1478–92.

  6. 6.

    Mahtta D, Elgendy AY, Elgendy IY, Mahmoud AN, Tobis JM, Mojadidi MK. Intravascular ultrasound for guidance and optimization of percutaneous coronary intervention. Interv Cardiol Clin. 2018;7(3):315–28.

    Article  PubMed  Google Scholar 

  7. 7.

    Schiele F, Meneveau N, Vuillemenot A, Zhang DD, Gupta S, Mercier M, et al. Impact of intravascular ultrasound guidance in stent deployment on 6-month restenosis rate: a multicenter, randomized study comparing two strategies--with and without intravascular ultrasound guidance. RESIST study group. REStenosis after Ivus guided STenting. J Am Coll Cardiol. 1998;32(2):320–8.

  8. 8.

    Fitzgerald PJ, Oshima A, Hayase M, Metz JA, Bailey SR, Baim DS, et al. Final results of the Can Routine Ultrasound Influence Stent Expansion (CRUISE) study. Circulation. 2000;102(5):523–30.

  9. 9.

    Mudra H, di Mario C, de Jaegere P, Figulla HR, Macaya C, Zahn R, et al. Randomized comparison of coronary stent implantation under ultrasound or angiographic guidance to reduce stent restenosis (OPTICUS study). Circulation. 2001;104(12):1343–9.

  10. 10.

    Gaster AL, Slothuus Skjoldborg U, Larsen J, Korsholm L, von Birgelen C, Jensen S, et al. Continued improvement of clinical outcome and cost effectiveness following intravascular ultrasound guided PCI: insights from a prospective, randomised study. Heart. 2003;89(9):1043–9.

  11. 11.

    Oemrawsingh PV, Mintz GS, Schalij MJ, Zwinderman AH, Jukema JW, van der Wall EE. Intravascular ultrasound guidance improves angiographic and clinical outcome of stent implantation for long coronary artery stenoses: final results of a randomized comparison with angiographic guidance (TULIP study). Circulation. 2003;107(1):62–7.

    Article  PubMed  Google Scholar 

  12. 12.

    Gil RJ, Pawlowski T, Dudek D, Horszczaruk G, Zmudka K, Lesiak M, et al. Comparison of angiographically guided direct stenting technique with direct stenting and optimal balloon angioplasty guided with intravascular ultrasound. The multicenter, randomized trial results. Am Heart J. 2007;154(4):669–75.

    Article  PubMed  Google Scholar 

  13. 13.

    Park SJ, Kim YH, Park DW, Lee SW, Kim WJ, Suh J, et al. Impact of intravascular ultrasound guidance on long-term mortality in stenting for unprotected left main coronary artery stenosis. Circ Cardiovasc Interv. 2009;2(3):167–77.

  14. 14.

    Parise H, Maehara A, Stone GW, Leon MB, Mintz GS. Meta-analysis of randomized studies comparing intravascular ultrasound versus angiographic guidance of percutaneous coronary intervention in pre-drug-eluting stent era. Am J Cardiol. 2011;107(3):374–82.

    Article  PubMed  Google Scholar 

  15. 15.

    Witzenbichler B, Maehara A, Weisz G, Neumann FJ, Rinaldi MJ, Metzger DC, et al. Relationship between intravascular ultrasound guidance and clinical outcomes after drug-eluting stents: the assessment of dual antiplatelet therapy with drug-eluting stents (ADAPT-DES) study. Circulation. 2014;129(4):463–70.

  16. 16.

    Chen SL, Ye F, Zhang JJ, Tian NL, Liu ZZ, Santoso T, et al. Intravascular ultrasound-guided systematic two-stent techniques for coronary bifurcation lesions and reduced late stent thrombosis. Catheter Cardiovasc Interv. 2013;81(3):456–63.

  17. 17.

    Gao XF, Kan J, Zhang YJ, Zhang JJ, Tian NL, Ye F, et al. Comparison of one-year clinical outcomes between intravascular ultrasound-guided versus angiography-guided implantation of drug-eluting stents for left main lesions: a single-center analysis of a 1,016-patient cohort. Patient Prefer Adherence. 2014;8:1299–309.

  18. 18.

    Chen L, Xu T, Xue XJ, Zhang JJ, Ye F, Tian NL, et al. Intravascular ultrasound-guided drug-eluting stent implantation is associated with improved clinical outcomes in patients with unstable angina and complex coronary artery true bifurcation lesions. Int J Card Imaging. 2018;34(11):1685–96.

  19. 19.

    Chieffo A, Latib A, Caussin C, Presbitero P, Galli S, Menozzi A, et al. A prospective, randomized trial of intravascular-ultrasound guided compared to angiography guided stent implantation in complex coronary lesions: the AVIO trial. Am Heart J. 2013;165(1):65–72.

  20. 20.

    Hong SJ, Kim BK, Shin DH, Nam CM, Kim JS, Ko YG, et al. Effect of intravascular ultrasound-guided vs angiography-guided everolimus-eluting stent implantation: the IVUS-XPL randomized clinical trial. JAMA. 2015;314(20):2155–63.

  21. 21.

    Kim BK, Shin DH, Hong MK, Park HS, Rha SW, Mintz GS, et al. Clinical impact of intravascular ultrasound-guided chronic total occlusion intervention with zotarolimus-eluting versus biolimus-eluting stent implantation: randomized study. Circ Cardiovasc Interv. 2015;8(7):e002592.

  22. 22.

    Tan Q, Wang Q, Liu D, Zhang S, Zhang Y, Li Y. Intravascular ultrasound-guided unprotected left main coronary artery stenting in the elderly. Saudi Med J. 2015;36(5):549–53.

    Article  PubMed  PubMed Central  Google Scholar 

  23. 23.

    Tian NL, Gami SK, Ye F, Zhang JJ, Liu ZZ, Lin S, et al. Angiographic and clinical comparisons of intravascular ultrasound- versus angiography-guided drug-eluting stent implantation for patients with chronic total occlusion lesions: two-year results from a randomised AIR-CTO study. EuroIntervention. 2015;10(12):1409–17.

  24. 24.

    Elgendy IY, Mahmoud AN, Elgendy AY, Bavry AA. Outcomes with intravascular ultrasound-guided stent implantation: a meta-analysis of randomized trials in the era of drug-eluting stents. Circ Cardiovasc Interv. 2016;9(4):e003700.

    CAS  Article  PubMed  Google Scholar 

  25. 25.

    Bavishi C, Sardar P, Chatterjee S, Khan AR, Shah A, Ather S, et al. Intravascular ultrasound-guided vs angiography-guided drug-eluting stent implantation in complex coronary lesions: meta-analysis of randomized trials. Am Heart J. 2017;185:26–34.

  26. 26.

    Shin DH, Hong SJ, Mintz GS, Kim JS, Kim BK, Ko YG, et al. Effects of intravascular ultrasound-guided versus angiography-guided new-generation drug-eluting stent implantation: meta-analysis with individual patient-level data from 2,345 randomized patients. JACC Cardiovasc Interv. 2016;9(21):2232–9.

  27. 27.

    Steinvil A, Zhang YJ, Lee SY, Pang S, Waksman R, Chen SL, et al. Intravascular ultrasound-guided drug-eluting stent implantation: an updated meta-analysis of randomized control trials and observational studies. Int J Cardiol. 2016;216:133–9.

  28. 28.

    Fujino Y, Bezerra HG, Attizzani GF, Wang W, Yamamoto H, Chamie D, et al. Frequency-domain optical coherence tomography assessment of unprotected left main coronary artery disease-a comparison with intravascular ultrasound. Catheter Cardiovasc Interv. 2013;82(3):E173–83.

    Article  PubMed  Google Scholar 

  29. 29.

    Habara M, Nasu K, Terashima M, Kaneda H, Yokota D, Ko E, et al. Impact of frequency-domain optical coherence tomography guidance for optimal coronary stent implantation in comparison with intravascular ultrasound guidance. Circ Cardiovasc Interv. 2012;5(2):193–201.

  30. 30.

    Kubo T, Akasaka T, Shite J, Suzuki T, Uemura S, Yu B, et al. OCT compared with IVUS in a coronary lesion assessment: the OPUS-CLASS study. JACC Cardiovasc Imaging. 2013;6(10):1095–104.

  31. 31.

    Giavarini A, Kilic ID, Redondo Dieguez A, Longo G, Vandormael I, Pareek N, et al. Intracoronary imaging. Heart. 2017;103(9):708–25.

    Article  PubMed  Google Scholar 

  32. 32.

    •• Ali ZA, Maehara A, Genereux P, Shlofmitz RA, Fabbiocchi F, Nazif TM, et al. Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a randomised controlled trial. Lancet. 2016;388(10060):2618–28. This study is notable because it is the first and only RCT to-date (to our knowledge) that has carried out a three-way comparison of OCT vs. IVUS vs. angiography for guiding DES implantation.

  33. 33.

    Campos CM, Garcia-Garcia HM, Iqbal J, Muramatsu T, Nakatani S, Dijkstra J, et al. Serial volumetric assessment of coronary fibroatheroma by optical frequency domain imaging: insights from the TROFI trial. Eur Heart J Cardiovasc Imaging. 2018;19(1):92–100.

  34. 34.

    Kimura S, Sagawa Y, Sugiyama T, Hishikari K, Nakamura S, Nakagama S, et al. Progression of a lesion with nodular calcification: serial observations by optical coherence tomography and coronary angioscopy. Coron Artery Dis. 2017;28(3):266–7.

  35. 35.

    Kataoka Y, Puri R, Hammadah M, Duggal B, Uno K, Kapadia SR, et al. Spotty calcification and plaque vulnerability in vivo: frequency-domain optical coherence tomography analysis. Cardiovasc Diagn Ther. 2014;4(6):460–9.

  36. 36.

    Yahagi K, Joner M, Virmani R. The mystery of spotty calcification: can we solve it by optical coherence tomography? Circ Cardiovasc Imaging. 2016;9:1.

    Article  Google Scholar 

  37. 37.

    Kim JS, Kang TS, Mintz GS, Park BE, Shin DH, Kim BK, et al. Randomized comparison of clinical outcomes between intravascular ultrasound and angiography-guided drug-eluting stent implantation for long coronary artery stenoses. JACC Cardiovasc Interv. 2013;6(4):369–76.

  38. 38.

    • Buccheri S, Franchina G, Romano S, Puglisi S, Venuti G, D'Arrigo P, et al. Clinical outcomes following intravascular imaging-guided versus coronary angiography-guided percutaneous coronary intervention with stent implantation: a systematic review and Bayesian network meta-analysis of 31 studies and 17,882 patients. JACC Cardiovasc Interv. 2017;10(24):2488–98. As one of the largest MAs in IVI-guidance, this study underscores the reduced risk for cardiovascular death and adverse events associated with IVI-guidance when compared to angiography alone.

  39. 39.

    •• Zhang J, Gao X, Kan J, Ge Z, Han L, Lu S, et al. Intravascular ultrasound versus angiography-guided drug-eluting stent implantation: the ULTIMATE trial. J Am Coll Cardiol. 2018;72(24):3126–37. While prior studies had focused on complex lesions and high-risk patient subsets, this RCT demonstrated that IVUS-guidance significantly reduces TVF in "all-comer" patients when compared to angiography alone.

  40. 40.

    • Darmoch F, Alraies MC, Al-Khadra Y, Moussa Pacha H, Pinto DS, Osborn EA. Intravascular ultrasound imaging-guided versus coronary angiography-guided percutaneous coronary intervention: a systematic review and meta-analysis. J Am Heart Assoc. 2020;9(5):e013678. As the largest MA in IVUS-guidance, this study was decisive in establishing the superior role of IVUS when compared to angiography alone.

  41. 41.

    Malik AH, Yandrapalli S, Aronow WS, Panza JA, Cooper HA. Intravascular ultrasound-guided stent implantation reduces cardiovascular mortality - updated meta-analysis of randomized controlled trials. Int J Cardiol. 2020;299:100–5.

    Article  PubMed  Google Scholar 

  42. 42.

    Elgendy IY, Mahmoud AN, Elgendy AY, Mintz GS. Intravascular ultrasound-guidance is associated with lower cardiovascular mortality and myocardial infarction for drug-eluting stent implantation- insights from an updated meta-analysis of randomized trials. Circ J. 2019;83(6):1410–3.

    Article  PubMed  Google Scholar 

  43. 43.

    •• Gao XF, Wang ZM, Wang F, Gu Y, Ge Z, Kong XQ, et al. Intravascular ultrasound guidance reduces cardiac death and coronary revascularization in patients undergoing drug-eluting stent implantation: results from a meta-analysis of 9 randomized trials and 4724 patients. Int J Card Imaging. 2019;35(2):239–47.

  44. 44.

    Kumar A, Shariff M, Adalja D, Doshi R. Intravascular ultrasound versus angiogram guided drug eluting stent implantation. A systematic review and updated meta-analysis with trial sequential analysis. Int J Cardiol Heart Vasc. 2019;25:100419.

    Article  PubMed  PubMed Central  Google Scholar 

  45. 45.

    Prati F, Di Vito L, Biondi-Zoccai G, Occhipinti M, La Manna A, Tamburino C, et al. Angiography alone versus angiography plus optical coherence tomography to guide decision-making during percutaneous coronary intervention: the Centro per la Lotta contro l’Infarto-optimisation of percutaneous coronary intervention (CLI-OPCI) study. EuroIntervention. 2012;8(7):823–9.

    Article  PubMed  Google Scholar 

  46. 46.

    • Kuku KO, Ekanem E, Azizi V, Melaku G, Bui A, Meirovich YF, et al. Optical coherence tomography-guided percutaneous coronary intervention compared with other imaging guidance: a meta-analysis. Int J Card Imaging. 2018;34(4):503–13. This study is notable because it is one of only two MAs comparing OCT-guided PCI with other imaging modalities; demonstrating its superiority to coronary angiography alone and non-inferiority to IVUS.

  47. 47.

    • Kubo T, Shinke T, Okamura T, Hibi K, Nakazawa G, Morino Y, et al. Optical frequency domain imaging vs. intravascular ultrasound in percutaneous coronary intervention (OPINION trial): one-year angiographic and clinical results. Eur Heart J. 2017;38(42):3139–47. This RCT was important for establishing the non-inferiority of OCT vs. IVUS-guided PCI for clinical outcomes at long-term follow-up.

  48. 48.

    Jones DA, Rathod KS, Koganti S, Hamshere S, Astroulakis Z, Lim P, et al. Angiography alone versus angiography plus optical coherence tomography to guide percutaneous coronary intervention: outcomes from the pan-London PCI cohort. JACC Cardiovasc Interv. 2018;11(14):1313–21.

  49. 49.

    Tanaka A, Imanishi T, Kitabata H, Kubo T, Takarada S, Tanimoto T, et al. Lipid-rich plaque and myocardial perfusion after successful stenting in patients with non-ST-segment elevation acute coronary syndrome: an optical coherence tomography study. Eur Heart J. 2009;30(11):1348–55.

  50. 50.

    Yonetsu T, Kakuta T, Lee T, Takahashi K, Yamamoto G, Iesaka Y, et al. Impact of plaque morphology on creatine kinase-MB elevation in patients with elective stent implantation. Int J Cardiol. 2011;146(1):80–5.

  51. 51.

    Lee T, Yonetsu T, Koura K, Hishikari K, Murai T, Iwai T, et al. Impact of coronary plaque morphology assessed by optical coherence tomography on cardiac troponin elevation in patients with elective stent implantation. Circ Cardiovasc Interv. 2011;4(4):378–86.

  52. 52.

    Kini AS, Motoyama S, Vengrenyuk Y, Feig JE, Pena J, Baber U, et al. Multimodality intravascular imaging to predict periprocedural myocardial infarction during percutaneous coronary intervention. JACC Cardiovasc Interv. 2015;8(7):937–45.

  53. 53.

    Wijns W, Shite J, Jones MR, Lee SW, Price MJ, Fabbiocchi F, et al. Optical coherence tomography imaging during percutaneous coronary intervention impacts physician decision-making: ILUMIEN I study. Eur Heart J. 2015;36(47):3346–55.

    Article  PubMed  PubMed Central  Google Scholar 

  54. 54.

    Prati F, Romagnoli E, Burzotta F, Limbruno U, Gatto L, La Manna A, et al. Clinical impact of OCT findings during PCI: the CLI-OPCI II study. JACC Cardiovasc Imaging. 2015;8(11):1297–305.

    Article  PubMed  Google Scholar 

  55. 55.

    Elgendy IY, Gad M, Jain A, Mahmoud AN, Mintz GS. Outcomes with intravascular ultrasound-guided drug eluting stent implantation for unprotected left main coronary lesions: a meta-analysis. Am J Cardiol. 2019;124(10):1652–3.

    Article  PubMed  Google Scholar 

  56. 56.

    Mintz GS. Intravascular ultrasound and outcomes after drug-eluting stent implantation. Coron Artery Dis. 2017;28(4):346–52.

    Article  PubMed  Google Scholar 

  57. 57.

    Antonsen L, Thayssen P, Maehara A, Hansen HS, Junker A, Veien KT, et al. Optical coherence tomography guided percutaneous coronary intervention with Nobori stent implantation in patients with non-ST-segment-elevation myocardial infarction (OCTACS) trial: difference in strut coverage and dynamic malapposition patterns at 6 months. Circ Cardiovasc Interv. 2015;8(8):e002446.

  58. 58.

    Kala P, Cervinka P, Jakl M, Kanovsky J, Kupec A, Spacek R, et al. OCT guidance during stent implantation in primary PCI: a randomized multicenter study with nine months of optical coherence tomography follow-up. Int J Cardiol. 2018;250:98–103.

  59. 59.

    Sheth TN, Kajander OA, Lavi S, Bhindi R, Cantor WJ, Cheema AN, et al. Optical coherence tomography-guided percutaneous coronary intervention in ST-segment-elevation myocardial infarction: a prospective propensity-matched cohort of the thrombectomy versus percutaneous coronary intervention alone trial. Circ Cardiovasc Interv. 2016;9(4):e003414.

  60. 60.

    Kim IC, Yoon HJ, Shin ES, Kim MS, Park J, Cho YK, et al. Usefulness of frequency domain optical coherence tomography compared with intravascular ultrasound as a guidance for percutaneous coronary intervention. J Interv Cardiol. 2016;29(2):216–24.

  61. 61.

    Smilowitz NR, Mohananey D, Razzouk L, Weisz G, Slater JN. Impact and trends of intravascular imaging in diagnostic coronary angiography and percutaneous coronary intervention in inpatients in the United States. Catheter Cardiovasc Interv. 2018;92(6):E410–e5.

    Article  PubMed  PubMed Central  Google Scholar 

  62. 62.

    Mintz GS. Intravascular imaging, stent implantation, and the elephant in the room. JACC Cardiovasc Interv. 2017;10(24):2499–501.

    Article  PubMed  Google Scholar 

  63. 63.

    Alberti A, Giudice P, Gelera A, Stefanini L, Priest V, Simmonds M, et al. Understanding the economic impact of intravascular ultrasound (IVUS). Eur J Health Econ. 2016;17(2):185–93.

  64. 64.

    van der Sijde JN, Karanasos A, van Ditzhuijzen NS, Okamura T, van Geuns RJ, Valgimigli M, et al. Safety of optical coherence tomography in daily practice: a comparison with intravascular ultrasound. Eur Heart J Cardiovasc Imaging. 2017;18(4):467–74.

  65. 65.

    Funatsu A, Hano Y, Kobayashi T, Nakamura S. TCT-348 efficacy of intravascular ultrasound guided minimum contrast percutaneous coronary intervention for chronic kidney disease patients. J Am Coll Cardiol. 2014;64(11 Supplement):B101.

    Article  Google Scholar 

  66. 66.

    Ali ZA, Karimi Galougahi K, Nazif T, Maehara A, Hardy MA, Cohen DJ, et al. Imaging- and physiology-guided percutaneous coronary intervention without contrast administration in advanced renal failure: a feasibility, safety, and outcome study. Eur Heart J. 2016;37(40):3090–5.

  67. 67.

    Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, et al. 2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and Interventions. Circulation. 2011;124(23):2574–609.

    Article  PubMed  Google Scholar 

  68. 68.

    • Ilumien Iv: Optimal Pci. This is an ongoing trial focused on high-risk, complex disease comparing outcomes after coronary stent implantation using OCT with routine coronary angiography.

  69. 69.

    Liu XM, Yang ZM, Liu XK, Zhang Q, Liu CQ, Han QL, et al. Intravascular ultrasound-guided drug-eluting stent implantation for patients with unprotected left main coronary artery lesions: a single-center randomized trial. Anatol J Cardiol. 2019;21(2):83–90.

    CAS  Article  PubMed  Google Scholar 

  70. 70.

    Meneveau N, Souteyrand G, Motreff P, Caussin C, Amabile N, Ohlmann P, et al. Optical coherence tomography to optimize results of percutaneous coronary intervention in patients with non-ST-elevation acute coronary syndrome: results of the multicenter, randomized DOCTORS study (does optical coherence tomography optimize results of stenting). Circulation. 2016;134(13):906–17.

  71. 71.

    Iannaccone M, D'Ascenzo F, Frangieh AH, Niccoli G, Ugo F, Boccuzzi G, et al. Impact of an optical coherence tomography guided approach in acute coronary syndromes: a propensity matched analysis from the international FORMIDABLE-CARDIOGROUP IV and USZ registry. Catheter Cardiovasc Interv. 2017;90(2):E46–e52.

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Correspondence to Adhir Shroff.

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Dr. Simon has nothing to disclose. Dr. Rodriguez Ziccardi has nothing to disclose. Ms. Dickens has nothing to disclose. Dr. Young has nothing to disclose. Dr. Shroff has nothing to disclose with relation to this manuscript.

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Simon, E.J., Ziccardi, M.R., Dickens, H. et al. Better Is the Evolution of Good: How IVUS and OCT Have Transformed PCI. Curr Cardiovasc Imaging Rep 13, 24 (2020).

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  • Clinical outcomes
  • Coronary angiography
  • Drug eluting stent
  • Intravascular imaging
  • Intravascular ultrasound
  • Optical coherence tomography
  • Optical frequency domain
  • Percutaneous coronary intervention