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Journal of Nuclear Cardiology

, Volume 24, Issue 1, pp 245–251 | Cite as

Comparison of the prognostic value of myocardial perfusion imaging using a CZT-SPECT camera with a conventional anger camera

  • Ronaldo Lima
  • Thais Peclat
  • Thalita Soares
  • Caio Ferreira
  • Ana Carolina Souza
  • Gabriel Camargo
Original Article

Abstract

Background

Recent studies have shown that myocardial perfusion imaging (MPI) in cadmium-zinc-telluride (CZT) cameras allow faster exams with less radiation dose but there are little data comparing its prognosis information with that of dedicated cardiac Na-I SPECT cameras

Objective

The objective of this study is to compare the prognostic value of MPI using an ultrafast protocol with low radiation dose in a CZT-SPECT and a traditional one.

Methods

Group 1 was submitted to a two-day MIBI protocol in a conventional camera, and group 2 was submitted to a 1-day MIBI protocol in CZT camera. MPI were classified as normal or abnormal, and perfusion scores were calculated. Propensity score matching methods were performed

Results

3554 patients were followed during 33±8 months. Groups 1 and 2 had similar distribution of age, gender, body mass index, risk factors, previous revascularization, and use of pharmacological stress. Group 1 had more abnormal scans, higher scores than group 2. Annualized hard events rate was higher in group 1 with normal scans but frequency of revascularization was similar to normal group 2. Patients with abnormal scans had similar event rates in both groups

Conclusion

New protocol of MPI in CZT-SPECT showed similar prognostic results to those obtained in dedicated cardiac Na-I SPECT camera, with lower prevalence of hard events in patients with normal scan.

Keywords

myocardial perfusion imaging coronary artery disease SPECT 

Abbreviations

MPI

Myocardial perfusion imaging

CAD

Coronary artery disease

SPECT

Single-photon emission computed tomography

CZT

Cadmium-zinc-telluride

BMI

Body mass index

PCI

Percutaneous coronary intervention

CABG

Coronary artery bypass surgery

Notes

Acknowledgments

The authors had no financial support for this research. The authors would like to thanks Dr. Ilan Gottlieb for his review and valuable suggestions.

Compliance with Ethical Standards

Disclosure

The authors declare that they have no conflict of interest.

Ethical standards

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments of comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Supplementary material

12350_2016_618_MOESM1_ESM.pptx (610 kb)
Supplementary material 1 (PPTX 610 kb)

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Copyright information

© American Society of Nuclear Cardiology 2016

Authors and Affiliations

  • Ronaldo Lima
    • 1
    • 2
  • Thais Peclat
    • 3
  • Thalita Soares
    • 3
  • Caio Ferreira
    • 3
  • Ana Carolina Souza
    • 3
  • Gabriel Camargo
    • 1
  1. 1.Department of CardiologyUniversidade Federal do Rio de JaneiroRio de JaneiroBrazil
  2. 2.Nuclear MedicineClínica de Diagnóstico por ImagemRio de JaneiroBrazil
  3. 3.Universidade Federal do Rio de JaneiroRio de JaneiroBrazil

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