Intestinal hypoganglionosis is a rare condition in adults. We report a case of intestinal hypoganglionosis in the mid-distal transverse colon to splenic flexure in a 65-year-old female patient presenting with altered bowel habit and abdominal distension, and reviewed the current literature on this topic. Our patient had a medical history of neurofibromatosis type 1. A preoperative computed tomography (CT) scan demonstrated a grossly dilated transverse colon without obstruction. A laparotomy for subtotal colectomy was performed, with histopathology demonstrating intestinal hypoganglionosis.
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Lee, A., Suhardja, T.S., Simpson, I. et al. Rare case of adult intestinal hypoganglionosis and review of the literature. Clin J Gastroenterol 14, 599–607 (2021). https://doi.org/10.1007/s12328-021-01342-5
- Intestinal hypoganglionosis
- Intestinal innervation disorder
- Colonic pseudo-obstruction