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Early stage clear cell adenocarcinoma of the colon examined in detail with image-enhanced endoscopy: a case report

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Abstract

Primary clear cell adenocarcinoma (CCA) of the colorectum is a rare tumor. We report on a 48-year-old man with early stage CCA in the descending colon who underwent detailed examination with image-enhanced endoscopy, such as magnifying endoscopy with narrow-band imaging and crystal violet staining. The tumor was treated successfully with endoscopic mucosal resection at our hospital.

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References

  1. Hellstrom HR, Fisher ER. Physaliferous variant of carcinoma of colon. Cancer. 1964;17:259–63.

    Article  CAS  Google Scholar 

  2. Reed RJ, Love GL, Harkin JC. Consultation case. Am J Surg Pathol. 1983;7:597–601.

    Article  CAS  Google Scholar 

  3. Jewell LD, Barr JR, McCaughey WT, et al. Clear cell epithelial neoplasms of the large intestine. Arch Pathol Lab Med. 1988;112:197–9.

    CAS  PubMed  Google Scholar 

  4. Rubio CA. Clear cell adenocarcinoma of the colon. J Clin Pathol. 1995;48:1142–4.

    Article  CAS  Google Scholar 

  5. Furman J. Clear cell change in colonic adenocarcinoma: an equally unusual finding. Histopathology. 1999;35:476–7.

    Article  CAS  Google Scholar 

  6. Stenzel P, Sauer D. Clear cell change in metastatic colonic adenocarcinoma. Histopathology. 2000;36:471–2.

    Article  CAS  Google Scholar 

  7. Braumann C, Schwabe M, Ordemann J, et al. The clear cell adenocarcinoma of the colon: case report and review of the literature. Int J Colorectal Dis. 2004;19:264–7.

    Article  Google Scholar 

  8. Soga K, Konishi H, Tatsumi N, et al. Clear cell adenocarcinoma of the colon: a case report and review of literature. World J Gastroenterol. 2008;14:1137–40.

    Article  Google Scholar 

  9. Barisella M, Lampis A, Perrone F, et al. Clear cell adenocarcinoma of the colon is a unique morphological variant of intestinal carcinoma. World J Gastroenterol. 2008;14:6575–7.

    Article  CAS  Google Scholar 

  10. Shi C, Scudiere JR, Cornish TC, et al. Clear cell change in colonic tubular adenoma and corresponding colonic clear cell adenocarcinoma is associated with an altered mucin core protein profile. Am J Surg Pathol. 2010;34:1344–50.

    Article  Google Scholar 

  11. Furuya Y, Wakahara T, Akimoto H, et al. Clear cell adenocarcinoma with enteroblastic differentiation of the ascending colon. J Clin Oncol. 2011;29:647–9.

    Article  Google Scholar 

  12. Bakshi N, Sharma S, Kaushal V, et al. Clear cell adenocarcinoma of the colon is a unique morphologic variant of intestinal carcinoma: a rare case report. Clin Cancer Investig J. 2012;1:173–5.

    Article  Google Scholar 

  13. Thelin C, Alquist CR, Engel LS, et al. Primary clear cell adenocarcinoma of the colon: a case report and review. J La State Med Soc. 2014;166:143–8.

    PubMed  Google Scholar 

  14. Barrera-Maldonado CD, Wiener I, Sim S. Clear cell adenocarcinoma of the colon: a case report and review of the literature. Case Rep Oncol Med. 2014; 2014:905478.

    PubMed  PubMed Central  Google Scholar 

  15. Mallik AA, Katchy KC. Clear cell adenocarcinoma of the rectum. Med Princ Pract. 2005;14:58–60.

    Article  CAS  Google Scholar 

  16. Ko YT, Baik SH, Kim SH, et al. Clear cell adenocarcinoma of the sigmoid colon. Int J Colorectal Dis. 2007;22:1543–4.

    Article  Google Scholar 

  17. Hao LS, Zhu X, Zhao LH, et al. Clear cell adenocarcinoma of colorectum: a case report and review of the literature. Acta Gastroenterol Belg. 2007;70:235–8.

    PubMed  Google Scholar 

  18. Wang W, Li X, Qu G, et al. Primary clear cell adenocarcinoma of the colon presenting as a huge extracolic mass. Oncol Lett. 2014;8:1873–5.

    Article  Google Scholar 

  19. Remo A, Grillo F, Mastracci L, et al. Clear cell colorectal carcinoma: time to clarify diagnosis. Pathol Res Pract. 2017;213:447–52.

    Article  Google Scholar 

  20. Suzuki H, Ohta S, Tokuchi S, et al. Adenoma with clear cell change of the large intestine. J Surg Oncol. 1998;67:182–5.

    Article  CAS  Google Scholar 

  21. Domoto H, Terahata S, Senoh A, et al. Clear cell change in colorectal adenomas: its incidence and histological characteristics. Histopathology. 1999;34:250–6.

    Article  CAS  Google Scholar 

  22. Eloy C, Lopes JM, Faria G, et al. Clear cell change in colonic polyps. Int J Surg Pathol. 2009;17:438–43.

    Article  Google Scholar 

  23. Sano Y, Tanaka S, Kudo SE, et al. Narrow-band imaging(NBI) magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert team. Dig Endosc. 2016;28:526–33.

    Article  Google Scholar 

  24. Kudo S, Tamura S, Nakajima T, et al. Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc. 1996;44:8–14.

    Article  CAS  Google Scholar 

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Correspondence to Katsumi Mukai.

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Tomomasa Tochio, Katsumi Mukai, Youichirou Baba, Hiroki Asakawa, Kenji Nose, Satomi Tsuruga, Hiroaki Kumazawa, Yoshiaki Isono, Hiroki Tanaka, Shimpei Matsusaki, Tomohiro Sase, Tomonori Saito, Hiroshi Okano, Miki Usui and Gen Watanabe declare that they have no conflict of interest.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from all patients for being included in the study.

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Tochio, T., Mukai, K., Baba, Y. et al. Early stage clear cell adenocarcinoma of the colon examined in detail with image-enhanced endoscopy: a case report. Clin J Gastroenterol 11, 465–469 (2018). https://doi.org/10.1007/s12328-018-0889-6

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  • DOI: https://doi.org/10.1007/s12328-018-0889-6

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